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Diss Factsheets
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EC number: 445-630-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study. However, assessment of biodegradability of multi-constituent substances has to be done by regarding the biodegradability of each constituent. Therefore, this study is used within a weight-of-evidence approach.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- -
- EC Number:
- 445-630-0
- EC Name:
- -
- Molecular formula:
- Unspecified
- IUPAC Name:
- 1-(acetyloxy)but-3-en-2-yl acetate; 2-hydroxybut-3-en-1-yl acetate
- Details on test material:
- - Name of test material (as cited in study report): Vinylglycoldiacetat, approx. 75 %
- Substance type: multi-constituent substance
- Physical state: liquid / colorless, clear
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Municipal activated sludge from the wastewater treatment plant of the city Mannheim/Baden, Württemberg (Germany), collected at 28 March 2006 from the aeration tank of theplant and aerated in the laboratory until use.
- Preparation of inoculum for exposure: Inoculum was sieved with by a finely woven mesh (mesh size about 1 mm), washed with
tap water and pre-aerated for about 24 hours.
- Pretreatment: None
- Concentration of sludge: 4 mg/L dry substance.
- Initial cell/biomass concentration:
- Type and size of filter used, if any: woven mesh (mesh size about 1 mm) - Duration of test (contact time):
- 28 d
- Details on study design:
- TEST CONDITIONS
- Composition of medium: mineral medium
- Test temperature: 22 ± 2 °C.
TEST SYSTEM
- Culturing apparatus: 160 mL incubation bottles filled up to a volume of 100mL.
- Number of culture flasks/concentration: 3
- Method used to create aerobic conditions: oxygen, available in the headspace of the bottles
- Measuring equipment: The carbon dioxide in the headspace is solved in the alkaline solution. The amount of Total Inorganic Carbon (TIC) was determined with a carbon analyzer.
- Test performed in closed vessels due to significant volatility of test substance: Yes
- Test performed in open system: No
- Details of trap for CO2 and volatile organics if used: carbon dioxide in the headspace is solved in the alkaline solution
SAMPLING
- Sampling frequency: every 4 days
- Sampling method: Total Inorganic Carbon (TIC) was determined with a carbon analyzer.
CONTROL AND BLANK SYSTEM
- Inoculum blank: Yes
- Abiotic sterile control: Yes
- Toxicity control: No
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (inorg. C analysis)
- Value:
- > 70 - < 80
- Sampling time:
- 28 d
- Remarks on result:
- other: 10-day window not met
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: The test substance is biodegradable.
- Executive summary:
The test performed by BASF (2006) indicates the multi-constituent substance to be biodegradable. However, as the reaction mass of 1,2-Diacetoxy-3-butene and 1,2-Dihydroxy-3-butene, monoacetate is a multi-constituent substance, the assessment of the biodegradability of the mixture has to be applied by regarding the biodegradation behaviour of each constituent. Due to the results of testing or QSAR it can be assumed, that all components are at least biodegradable or readily biodegradable (according to OECD criteria). Only 3-Octylacetate, CAS-No. 4864-61-3 was calculated by use of QSAR to be moderately biodegradable (ca. 30% BOD/ThOD). With a median amount of 0,3%, this substance should be regarded as negligible for the overall assessment of the biodegradability of the multi-constituent substance.
Overall it can be stated, that the reaction mass of 1,2-Diacetoxy-3-butene and 1,2-Dihydroxy-3-butene, monoacetate is biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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