Registration Dossier
Registration Dossier
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EC number: 242-551-1 | CAS number: 18742-02-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-(2-bromoethyl)-1,3-dioxolane
- EC Number:
- 242-551-1
- EC Name:
- 2-(2-bromoethyl)-1,3-dioxolane
- Cas Number:
- 18742-02-4
- Molecular formula:
- C5H9BrO2
- IUPAC Name:
- 2-(2-bromoethyl)-1,3-dioxolane
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- occlusive
- Preparation of test site:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Controls:
- other: same animal
- Observation period:
- 1hour, 24h, 48h, 72h.
- Number of animals:
- 3
Results and discussion
In vivo
Results
- Irritation parameter:
- erythema score
- Remarks:
- IPc = 2,5
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant)
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Irritant for the skin.
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