Registration Dossier
Registration Dossier
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EC number: 232-259-2 | CAS number: 7803-49-8
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publication which meets basic scientific principles.
Data source
Reference
- Reference Type:
- publication
- Title:
- Detection of free radicals as intermediates in the methemoglobin formation from oxyhemoglobin induced by hydroxylamine.
- Author:
- Stolze, K. and Nohl, H.
- Year:
- 1 989
- Bibliographic source:
- Biochemical Pharmacology, 39(18), 3055-3059
Materials and methods
- Principles of method if other than guideline:
- Electron spin resonance spectroscopy was used to detect the intermediates which were involved in the methemoglobin formation from bovine oxyhemoglobin induced by hydroxylamine.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Hydroxylamine
- EC Number:
- 232-259-2
- EC Name:
- Hydroxylamine
- Cas Number:
- 7803-49-8
- Molecular formula:
- H3NO
- IUPAC Name:
- hydroxylamine
- Details on test material:
- - Name of test material (as cited in study report): hydroxylamine (not further specified)
Constituent 1
- Radiolabelling:
- no
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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