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Diss Factsheets
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EC number: 941-717-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Antimicrobial activities of essential oils of mint and peppermint as well as some of their main compounds
- Author:
- Jivoretz L, Buchbauer G, Bail S, Denkova Z, Slachev A, Stoyanova A, Schmidt E, Geissler M
- Year:
- 2 009
- Bibliographic source:
- Dossier CAS 14073-97-3 (Journal of Essential Oil Research 21, 363-366 )
Materials and methods
- Principles of method if other than guideline:
- The antimicrobial activity was studied with the agar diffusion disc method using 6 mm paper discs and quantities of 6 µL of substance. After cultivation of the bacteria and the yeast at 37 °C for 24 h, the diameter of the inhibition zone (IZ) was measured. Then, the agar serial tube dilution method was applied, yielding results as minimum inhibitory concentration (MIC) as follows: The oil and pure reference compounds were added to brine, containing 1.0% (v/v) Tween 80 at the appropriate volumes to produce final concentrations of the samples in the range of 1-1000 ppm; the Petri dishes were inoculated by pipetting 0.1 cm3 of the bacterial or yeast culture and 6 µL of the test or reference compounds on paper discs (6 mm) and then incubated at 37°C for 24 h.
- GLP compliance:
- no
Test material
- Reference substance name:
- (-)-menthone
- IUPAC Name:
- (-)-menthone
- Details on test material:
- - Name of test material (as cited in study report): (-)-menthone
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Salmonella sp., Candida albicans
- Details on inoculum:
- All test microorganims were obtained from the National Bank of Industrial Microorganisms and Cell Cultures, Sofia, Bulgaria
Study design
- Test type:
- static
- Total exposure duration:
- 24 h
Test conditions
- Test temperature:
- 37 °C
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 60 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Staphylococcus aureus
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 60 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Enterococcus faecalis
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 600 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Escherichia coli
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 60 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Proteus vulgaris
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 600 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Klebsiella pneumoniae
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 60 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Salmonella sp.
- Duration:
- 24 h
- Dose descriptor:
- other: Minimum Inhibitory Concentration (MIC)
- Effect conc.:
- 60 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: Candida albicans
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.