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EC number: 410-070-8 | CAS number: 141880-36-6 ACID RED HT 3728; ERIONYL RED HT 3728
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 August 1992 to 15 January 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Directive No. L251 C.1, 1984
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code number: FAT 45155/B
Batch number: TV1
Appearance: solid
Solubility: ~100g/l (in water) [estimation]
Storage: room temperature + light protected
Expiration date: 15.5.1997 - Analytical monitoring:
- yes
- Details on sampling:
- Samples were taken every 24 hours for water quality measurement.
- Vehicle:
- no
- Details on test solutions:
- Test concentrations in definitive test: 17.8, 32, 56, 178 and 316 mg/L of nominal.
A control was carried out.
Mode of preparation: The test substance was disolved in 200 mL water, which was slowly added to the fish bath. - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Test organism: Zebra fish (Brachydanio rerio)
Weight: 1.7 g
Length: 26.0 mm
Age: 83 days
Acclimation: 19 days in dechlorinated tap water
Supplier: west Aquarium, Bad Lauterberg, BRD - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 179 mg/L (as CaCO3)
- Test temperature:
- 21-25 °C
- pH:
- 7.2-8.5
- Dissolved oxygen:
- 87-99 %
- Salinity:
- no data
- Nominal and measured concentrations:
- nominal: 17.8, 32, 56, 178 and 316 mg/L
measured: 101-113 % of nominal - Details on test conditions:
- Vessels: 5 L gass aquaria
Volume: 2.9 L
Diluent: dechlorinated tap water
Aeration: Slowly aerated - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 35 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 79 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 192 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 35 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - Mortality of control: No mortality occurred in the blank control
- Reported statistics and error estimates:
- The LC50 value were calculated with the Spearmann-Karber Method.
- Sublethal observations / clinical signs:
Abnormal responses of the fish: At concentrations of 100 and 178 mg/L (nominal) a slim change in the swimming behaviour of the test fish could be observed.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 and NOEC of FAT 45155/B are 79 and 35 mg/L, respectively.
- Executive summary:
The test was performed to determine the acute toxicity of test substance to Zebra fish during 96 hours according to OECD TG 203. 17.8, 32, 56, 100, 178 and 316 mg/L of test substances were applied in the definitive test. No mortality for control was observed at the end of the test. At concentrations of 100 and 178 mg/L (nominal) a slim change in the swimming behaviour of the test fish could be observed. Based on the study results, the LC0, LC50, LC100 of FAT 45155/B were 35, 79 and 192 mg/L, respectively. The NOEC was 35 mg/L.
Reference
Description of key information
The test was performed to determine the acute toxicity of test substance to Zebra fish during 96 hours according to OECD TG 203. 17.8, 32, 56, 100, 178 and 316 mg/L of test substances were applied in the definitive test. No mortality for control was observed at the end of the test. At concentrations of 100 and 178 mg/L (nominal) a slim change in the swimming behaviour of the test fish could be observed. Based on the study results, the LC0, LC50, LC100 of FAT 45155/B were 35, 79 and 192 mg/L, respectively. The NOEC of test substance was 35 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 79 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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