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EC number: 928-812-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Acute Toxicity-Oral LD50 > 4150 mg/kg in rats (OECD TG 401)
Acute Toxicity-Dermal LD50 > 1700 mg/kg in rabbits (OECD TG 402)
Acute Toxicity-Inhalation LC50 > 5.28 mg/L (OECD TG 403)
Key value for chemical safety assessment
Additional information
There are no data available for hydrocarbons, C13-C20, n-alkanes, isoalkanes, cyclics, 40-60% aromatics. However, there are data available for the analogue substances C14-C20 aliphatic, 2-30% aromatic hydrocarbon fluids and C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%). All of the animal studies were performed in a manner similar or equivalent to currently established OECD guidelines.
Oral
Hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) were tested in a fixed dose procedure by DHC Solvent Chemie GmbH in 1985. No rat died after a single administration of 5 mL/kg bodyweight test substance; converted to 4150 mg/kg bw, by oral gavage. The LD50 value was therefore greater than 4150 mg/kg bw.
Inhalation
The acute toxicity of hydrocarbons, C14-C20 aliphatics (2-30% aromatics) upon inhalation was tested in rats exposed to 5.28 +/- 0.42 mg/L to the whole body as vapour for 4 hours (American Petroleum Institute, 1985). Decreased activity was exhibited by all animals, but no mortality occurred during the exposure. Similar results were concluded from studies of Carpenter et al., summarized by American Petroleum Institute, 2003. No mortalities were observed in rats exposed to saturated vapour for 8 hours. Therefore, the LC50 value in rats was greater than 5.28 mg/L.
Dermal
Hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) were applied on the trunk of each of five male and five female rats via an occluded patch (DHC Solvent Chemie GmbH, 1985). The patch was removed 24 hours later. The exposure had no effect on viability. The LD50 value was > 2 mL/kg (converted 1.7 g/kg bodyweight). Straight run kerosene (CAS No. 8008-20-6) as undiluted test material was applied to abraded and intact skin of New Zealand White Rabbits (2/sex and dose) (American Petrolium Insitute, 1985). 24 hour exposure to 2 g/kg bw test substance caused hypoactivity and diarrhea as well as some skin effects. No animal died during the study (American Petroleum Institute, 1985). Therefore, the LD50 is higher than 2000 mg/kg bw.
Based on the available read-across data, C13-C20 aliphatic and cyclic, 40-60% aromatic hydrocarbons are considered to have at most a low order of acute toxicity by the oral, dermal, and inhalation routes of exposure.
The following information is taken into account for any hazard / risk assessment:
Acute Toxicity-Oral LD50 > 4150 mg/kg in rats (OECD TG 401)
Acute Toxicity-Dermal LD50 > 1700 mg/kg in rats (OECD TG 402)
Acute Toxicity-Inhalation LC50 > 5.28 mg/L (OECD TG 403)
Justification for classification or non-classification
The available data on the acute toxicity of structurally related substances are conclusive but not sufficient for classification. However, C13-C20 aliphatic and cyclic, 40-60% aromatic hydrocarbons pose an aspiration hazard.
C13-C20, n-alkanes, isoalkanes, cyclics, 40-60% aromatics are classified under EU CLP guidelines as a Category 1 aspiration hazard based on its physical and chemical properties (hydrocarbon fluid, viscosity is 3.86 to 8.88 mm2/s at 20° C≤ 20.5 mm2/s) and as an R65 aspiration hazard under the EU DSD/DPD.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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