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Diss Factsheets
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EC number: 203-005-8 | CAS number: 102-09-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short term toxicity to fish
The toxicity of diphenyl carbonate to fish (Danio rerio) was assessed according to EU Method C.1 (Bayer, 1994). The effective concentrations LC0 and LC100 were determined to be 0.91 and 5.6 mg/L, respectively (geometric mean over time). By graphic interpolation (linear) the resulting 96 h LC50 was determined to 3.9 mg/L.
Short term toxicity to aquatic invertebrates
The toxicity of diphenyl carbonate to aquatic invertebrates (Daphnia magna) was assessed according to EU Method C.2 (Bayer, 1999a). The effective concentration 48 h EC50 was determined to be 6.5 mg/L by graphic interpolation (linear).
Toxicity to aquatic algae
The toxicity of diphenyl carbonate to algae (Desmodesmus subspicatus) was assessed according to EU Method C.3 (Bayer, 1999b). A 72 h NOEC for growth rate of 0.22 mg/L (effective concentration) and an EC50 of 0.9 mg/L (effective concentration) were determined.
Assessment of the aquatic toxicity should however consider the uncertainty in the reported results. There does not appear to be sufficiently robust information available to warrant the use of the reported EC50 value of 0.9 mg/L for classification purposes concerning environmental toxicity hazard, as this is an estimated effective concentration.
In the supporting study (Smithers, 2010), the toxicity of the test material to algae was calculated using ECOSAR v1.00 (EPI Suite v4.0) March 2009. The predicted EC50 for green algae is 3.66 mg/L (96 h).
As a conclusion from the hazard assessment, when both the key and supporting data are taken into consideration, the toxicity of diphenyl carbonate towards algae is considered be with an EC50 value > 1 mg/L.
Toxicity to microorganisms
The toxicity of diphenyl carbonate to activated sludge was assessed using methodology comparable to OECD 209 (Bayer, 2000c). A 3 h EC10 of 60 mg/L and a 3 h EC50 of 4510 mg/L were determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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