Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-445-0 | CAS number: 106-94-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Eye contact: Holding the eyelids apart, flush eyes promptly with copious flowing water for at least 20 minutes. Get medical attention immediately.
Skin contact: Remove contaminated clothing. Wash skin thoroughly with mild soap and plenty of water for at least 15 minutes. Wash clothing before re-use. Get medical attention immediately.
Inhalation: In case of mist inhalation or breathing fumes released from heated material, remove person to fresh air. Keep him quiet and warm. Apply artificial respiration if necessary and get medical attention immediately.
Ingestion: If swallowed, wash mouth thoroughly with plenty of water and give water to drink. Get medical attention immediately.
Never give an unconscious person anything to drink.
Notes to the physician: Irritant. In case of inhalation may cause CNS toxicity. No specific antidote. Treat symptomatically and supportively.
Fire-fighting measures
Suitable extinguishing media: Carbon dioxide, dry chemical powder, alcohol foam or polymer foam. Water may be effective for cooling but not for extinguishing.
Fire fighting procedure: Cool containers with water spray. In closed stores, provide fire-fighters with self-contained breathing apparatus in positive pressure mode
Unusual fire and explosion hazards: Forms flammable mixtures with air in a narrow flammability range. Containers may explode when involved in a fire. When heated to decomposition, may release poisonous and corrosive fumes of HBr, CO and CO2.
Accidental release measures
Personal precautions: Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves.
Methods for cleaning up: Shut off all sources of ignition. Absorb on sand or vermiculite and place in closed container for disposal. Transport outdoors. Ventilate area and wash spill site after material pickup is complete.
Handling and storage
Handling: Keep containers tightly closed. Avoid bodily contact.
Storage: Store in a dry, cool, well-ventilated area away from incompatible materials (strong oxidizers, strong bases and aluminum). Keep away from heat, sparks and open flame.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- None
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- None
Shipping information
- Proper shipping name and description:
- Not regulated
- Chemical name:
- Not regulated
- Labels:
- Not regulated
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Exposure controls / personal protection
Exposure Limits
Components: 1-BROMOPROPANE (106-94-5)
Weight % : >99
ACGIH-TLV Data: 10 ppm
Netherlands national MAC data: Not determined
UK (WEL) - TWA: Not determined
Ventilation requirements: Ventilation must be sufficient to maintain atmospheric concentration below recommended exposure limit.
Personal protective equipment:
- Respiratory protection: Approved respirator
- Hand protection: Protective gloves
- Eye protection: Chemical safety goggles or face shield with safety glasses.
When used as an intermediate, this substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.
Stability and reactivity
Stability: Stable under normal conditions After a year may become acidic with some HBr forming.
Materials to avoid: Strong oxidizers and strong bases, Aluminum
Conditions to avoid: Keep away from heat, sparks and open flame
Hazardous decomposition products: Hydrogen bromide, carbon dioxide and carbon monoxide
Hazardous polymerization: Will not occur
Disposal considerations
Waste disposal: Observe all federal, state and local environmental regulations when disposing of this material.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.