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Diss Factsheets
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EC number: 247-148-4 | CAS number: 25637-99-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
In the environment, HBCDD is predicted to partition to soil and sediment (approximately 98%) where it will bind extensively to organic carbon (estimated Koc soil 1.25 x 105) and to be essentially immobile in soil. Aerobic and anaerobic biodegradation in soil and sediment has been demonstrated in microcosms. At low concentrations (ng/g), degradation in anaerobic soil and sediment was rapid with half-lives of 6.9 and 1 day(s) respectively. The aerobic sediment half-life was approximately 1 day. At higher concentrations (mg/kg), no degradation was noted in aerobic soil. The same three degradants as determined in sludge were identified for soil and sediment. Additionally, mineralisation to CO2 was observed. At low concentrations (ng/g), the three HBCDD diastereomers were all found to degrade in aerobic soil with half-lives dependent on the diastereomer and soil type. Thus, biodegradation of HBCDD in anaerobic soils is rapid with a half-life of approximately 7 days. Slower biodegradation was observed in aerobic soils with an overall half-life of 63 days for HBCDD and half-lives of 162 or 441, 64 or 147 and 126 or 201 days for the alpha, beta and gamma diastereomers.
HBCDD is not expected to volatilise from water based on its river and lake volatilisation half-lives and air-water partition coefficient. HBCDD is expected to partition from water to organic matter (biomass to water partition coefficient 1 x 107). Sewage treatment plants are predicted to remove HBCDD from the influent to a high degree (94% removal) via partitioning to sludge. Aerobic biodegradation in the treatment plant is not expected and HBCDD was not found to be readily biodegradable. Degradation in the anaerobic digester of treatment plants is expected and has been observed in testing.
HBCDD was inherently biodegradable by digester sludge via a sequestration dihalo-elimination with the formation of three degradants (tetrabromocyclododecane, dibromocyclododecadiene and cyclododecatriene). The half-life in sludge was related to concentration: 0.66 days at very low concentration and 15 days at high concentration.
HBCDD's steady-state whole body fish BCF was 8794. Steady-state was reached after a 35 day exposure via water. Applying a kinetic method of calculation, a BCF of 21940 (whole body dry weight) after 35 days exposure was calculated.
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