Registration Dossier
Registration Dossier
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EC number: 208-909-6 | CAS number: 546-68-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Testing is not scientifically justified as this substance is hydrolytically unstable and the decomposition products possess low aquatic toxicity. The read-across result of the 16-h toxicity threshold of isopropyl alcohol (IPA) to Pseudomonas putida (cell multiplication); 1050 mg/l, based on the nominal concentrations, is used as key value in CSA.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 050 mg/L
Additional information
According to the ECHA Guidance on information requirements and chemical safety assessment, in absence of activated respiration test, toxicity results to microbial bacteria can be used for evaluate the inhibitory effects of chemicals to STP micro-organisms. Therefore, the result of the P.putida cell multiplication inhibition test of the organic hydrolysing product (IPA) with Klimisch score 2 is used to calculate the PNEC STP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
