Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 205-391-3 | CAS number: 140-01-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-hour EC50 for Daphnia carinata, a freshwater species, was 245 mg/L DTPA, which is equivalent to 310 mg/L pentasodium DTPA. The 96-hour LC50 for Crangon crangon, a saltwater species, was 6020 mg/L pentasodium DTPA.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 310 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 6 020 mg/L
Additional information
Four acute toxicity tests with aquatic invertebrates were assessed for this endpoint, and all four studies were found to be of good quality and reliable for use in the risk assessment process. Two studies were conducted with the freshwater cladoceran, Daphnia magna, one study was conducted with the freshwater cladoceran, Daphnia carinata,and one study was conducted with the marine brown shrimp, Crangon crangon. Both the pentapotassium and pentasodium DTPA salts as well as DTPA (free acid) were used as test substances in these exposure studies. Since the pentapotassium and pentasodium salts of DTPA dissociate when in contact with water, these salts are considered equivalent to DTPA (free acid) in aquatic environments. The 48-hour EC50 values for D. magna (after stoichiometric conversion from pentapotassium DTPA to pentasodium DTPA) ranged from > 500 to 760 mg/L pentasodium DTPA, while the EC50 value for D. carinata (after stoichiometric conversion from DTPA free acid to pentasodium DTPA) was 310 mg/L DTPA. The 96 -hour LC50 for the brown shrimp, Crangon crangon, was 6020 mg/L pentasodium DTPA. The key parameter for the freshwater studies was the EC50 value of 310 mg/L reported for D. carinata, since this is the lowest acute toxicity value reported for a freshwater invertebrate species. The key parameter for the saltwater studies was the 96-hour LC50 value of 6020 mg/L reported for the brown shrimp.
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