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Diss Factsheets
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EC number: 210-323-0 | CAS number: 612-83-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Stability:
All available studies relating to stability had been performed with the base of the submission substance, 3,3´-dichlorobenzidine (DCB).
DCB is stable against hydrolysis at different pH-values. However, sunlight and, to a lesser extent UV-light, is capable of inducing fast phototransformation in air as well as in water (water: 70% transfromation in 10 minutes). In water, via the transient products monochlorobenzidine and benzidine, in water unsoluble coloured compounds are formed.
Biodegradation:
In the key study, 3,3´-dichlorobenzidine was tested for "ready biodegradablilty" in a sound and sufficiently well documented study (relibility score 2, reliable with restrictions) according to the OECD-guideline 301 A (AFNOR method) with deviations especially regarding substance concentration (much lower, because of the poor water solubility) and analytics (spectroscopic monitoring of substance concentration). The study results, constituted by the single results of serveral different laboratories taking part, demonstrate, that 3,3´-dichlororbenzidine is not readily biodegradable under the applied conditions (0% degradation at the end of the observation period). Experimental results pointing to inherent biodegradability in the presence of yeast extract as an external carbon source are rather to be seen as the result of the inherently strong adsoprtion potential of DCB to organic matter, which results in the withdrawal from the water phase.
Bioaccumulation:
Reported bioaccumulation factors (DCB) are especially high for activated sewage sludge (BAF = 3100, related to dry weight) and for green algae (BAF = 940, related to fresh weight). For fish, BAF between 500 and 600 have been reported.
Transport and distribution:
Adsorption/Desoprtion:
3,3´-dichlorobenzidine (DCB) is readily adsorbed by aquatic sediments. Depending on the carbon content, sediment-water partition coefficients between 20 to 128 have been determined. With prolonged contact time, a transition from physical adsorption to covalent bonds by condensation reactions of amino groups of DCB with carbonyl groups of the organic carbon content of the sediment might be the reason for the ever reduced desoprtion observed with time.
Henry´s law constant:
H (3,3´-dichlororbenzidine) = Ps/Cs = 5*10(-5) Pa * m3 * mol(-1) (at 20 -25 °C); therefore, volatility of DCB form aquatic solutions is expected to be low.
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