Registration Dossier
Registration Dossier
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EC number: 231-781-8 | CAS number: 7727-21-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- READ ACROSS CATEGORY APPROACH
A category group was formed with dipotassium peroxodisulphate (KPS), disodium peroxodisulphate (SPS) and diammonium peroxodisulphate (APS). Several physico-chemical, fate, ecotoxicological and toxicological endpoints were assessed using the category approach. Please refer to the read across justification in chapter 13 for further information. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 18 h
- Dose descriptor:
- EC10
- Effect conc.:
- 36 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: multiplication of bacterial cells
Reference
Description of key information
No studies on toxicity to microorganisms with dipotassium persulfate were available. A read across approach was applied to studies with diammonium persulfate, as the substance shows similar ecotoxicological properties. The toxicity of microorganisms to diammonium persulfate was tested in a study according to guidelines NEN 6509 and NPR 6508. The study revealed an EC10 (18 h) of 36 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 36 mg/L
Additional information
No study on toxicity to microorganisms with dipotassium persulfate was available. Instead a read across approach was applied to assess the toxicity to microorganisms using data available for diammonium persulfate, a substance considered to exhibit comparable ecotoxicological properties. In the key study the toxicity of diammonium persulfate to the gram negative bacterium Pseudomonas putida was determined in a growth inhibition test according to guidelines NEN 6509 and NPR 6508. Bacteria were exposed in a static test to concentrations of diammonium persulfate up to 100 mg/L. The study revealed an EC10 (18 h) of 36 mg/L.
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