Registration Dossier
Registration Dossier
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EC number: 906-256-8 | CAS number: -
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
monoethylene glycol: 7day NOEC=15380. Triethylene glycol: 28 day LC50>1500mg/l
QSAR values: 2630, 7690, 18640mg/l respectively (30 day Chv values) for MEG, DEG and TEG.
Key value for chemical safety assessment
Additional information
There is chronic toxicity data on two of the three constituents of this substance (those that represent the structural extremes.) However, neither study is ideal. One presents a NOEC but is only a 7 day study, whilst the latter is of an appropriate duration but only presents an LD50. QSAR data suggests that the toxicity decreases with increasing molecular weight and therefore that monoethylene glycol is likely to be the most toxic species. Overall, it is clear that all of the components present very low chronic toxicity. A weight of evidence approach suggest that a 28 day NOEC is likely to be well in excess of 1000mg/l and that fish are the least sensitive of the three trophic levels.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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