Registration Dossier
Registration Dossier
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EC number: 209-980-6 | CAS number: 600-00-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.1 bis (Acute Oral Toxicity - Fixed Dose Procedure)
- GLP compliance:
- yes (incl. QA statement)
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- Ethyl 2-bromo-2-methylpropionate
- EC Number:
- 209-980-6
- EC Name:
- Ethyl 2-bromo-2-methylpropionate
- Cas Number:
- 600-00-0
- Molecular formula:
- C6H11BrO2
- IUPAC Name:
- ethyl 2-bromo-2-methylpropionate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Doses:
- Single administration
- No. of animals per sex per dose:
- 4 femals
- Control animals:
- no
Results and discussion
- Preliminary study:
- No mortalities at dose levels of 300 and 2000 mg/kg bw.
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- >= 2 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute oral median lethal dose (LD50) of the test material in the female Sprague-Drawley CD strain rat was estimated to be greater than 2000 mg/kg bodyweight.
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