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Diss Factsheets

Ecotoxicological information

Toxicity to soil microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The test substance causes adverse effects on nitrate production in soil.

Key value for chemical safety assessment

Long-term EC10 or NOEC for soil microorganisms:
115.3 mg/kg soil dw

Additional information

The toxicity to soil microorganisms was determined in a study according to OECD guideline No 216 and in compliance with GLP criteria. In this 28-day toxicity study, natural soil was exposed to the test substance at nominal concentrations of 0 (control), 62.5, 125, 250, 500 and 1000 mg/kg (dry weight) under conditions in accordance with the guidelines. The amount of nitrate formed by microbial processes was determined at start of exposure, after 7, 14 and after 28 days at the end of exposure. The results of the nitrate analyses of the treated replicates were compared to control assays and the nitrate production in the treated replicates was expressed as an inhibition of the process of nitrogen oxidation. On day 28 the EC10 and EC50 values were determined to be 115 mg/kg dry weight and 792.3 mg/kg dry weight, respectively.