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EC number: 203-931-2 | CAS number: 112-05-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study initiation date: 29 July 2009 Study completion date:10. November 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted on 27 July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Directive 92/69/EEC, Official Journal L 383 A 1992
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 0.27 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 6.67 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 4.2
- Remarks on result:
- other: samples were shaken at 30°C for 24, 48 and 72 h, respectively, then equilibrated at 20 ± 0.5 °C
- Details on results:
- The purified water used for the tests had a pH value of 7.06
- Conclusions:
- Water Solubility (OECD 105; flask method): 0.27 g/L at 20 °C (pH 4.2)
- Executive summary:
The water solubility of the test item was determined according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method (AQura, 2009).
Water solubility (at 20 °C): 0.27 g/L (pH 4.2)
Reference
Preliminary test
The test item was dissolved in the pre-sample with a concentration of approx. 10E-02 g/L (10 µl/L equivalent to 9 mg/L based on density: 0.905 g/cm^3).
Thus the flask method was performed.
Main test, results:
Sample no. | Amount of test item [mg] |
Added volume of water [mL] | Shaking time at 30°C [h] | Analysed carbon concentration [mg C/L] |
Concentration of the test item[mg/L]1) | pH value2) |
1 | 127 | 15 | 24 | 190 | 0.28 | 4.4* |
2 | 124 | 15 | 24 | 186 | 0.27 | 4.3* |
3 | 135 | 15 | 48 | 160 | 0.24 | 4.2 |
4 | 128 | 15 | 48 | 174 | 0.26 | 4.2 |
5 | 121 | 15 | 72 | 191 | 0.28 | 4.2 |
6 | 129 | 15 | 72 | 189 | 0.28 | 4.2 |
1) calculated from the carbon concentration of the sample solutions and the carbon content of the pure test item (67.8 %)
2) The purified water used for the tests had a pH value of 7.06.
*) The samples had to be diluted (1 ml sample + 3 ml water) for the pH-determination due to a too small sample volume.
Descriptive statistics for samples one to 6:
- arithmetic mean value: 0.27 g/L
- standard deviation (SD): 0.02 g/L
- relative SD: 5.97%
Water solubility as a function of time:
- n=2 after 24 h at 30 °C: 0.28 g/L;
- n=2 after 48 h at 30 °C: 0.25 g/L
- n=2 after 72 h at 30 °C: 0.28 g/L
The relative standard deviation (repeatability) of the concentrations in all six samples was smaller than 15 % and the three duplicate sets of samples showed no tendency of increasing concentration
values. Thus the test was satisfactory.
Description of key information
Water Solubility (OECD 105; flask method): 0.27 g/L at 20 °C (pH 4.2)
Key value for chemical safety assessment
- Water solubility:
- 0.27 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test item was determined according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method (AQura, 2009).
Water solubility (at 20 °C): 0.27 g/L (pH 4.2)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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