Registration Dossier
Registration Dossier
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EC number: 200-306-6 | CAS number: 57-00-1
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Data waiving:
- other justification
- Justification for data waiving:
- the study does not need to be conducted because the melting point is above 300°C
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- Value published in Hazardous Substancea Data Bank (HSDB).
- Qualifier:
- no guideline followed
- GLP compliance:
- no
- Type of method:
- other: QSAR calculation
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 mm Hg
- Conclusions:
- The calculated value for the vapour pressure of creatine is 7.9E-4 mm Hg at 25 °C.
- Executive summary:
No measured data are availbale regarding creatine (CAS 57-00-1) vapour pressure.
However, the Hazardous Substances Data Bank (HSDB) reports a peer-reviewed, calculated value of 7.9E-4 mm Hg at 15 °C (estimation program: US EPA, Estimation Programs Interface (EPI). ver. 3.11. U.S. EPA version for windows. Washington, DC: U.S. EPA (2003). Available from, as of Apr 27, 2005: http://www.epa.gov/oppt/exposure/pubs/episuitedl.htm)
Referenceopen allclose all
Description of key information
In accordance with REACH Annex VII, column 2, the study does not need to be conducted as the melting point is above 300 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0.105 Pa
- at the temperature of:
- 25 °C
Additional information
No measured data are available regarding creatine (CAS 57-00-1) vapour pressure.
However, the Hazardous Substances Data Bank (HSDB) reports a peer-reviewed, calculated value of 7.9E-4 mm Hg at 15 °C (estimation program: US EPA, Estimation Programs Interface (EPI). ver. 3.11. U.S. EPA version for windows. Washington, DC: U.S. EPA (2003). Available from, as of Apr 27, 2005: http://www.epa.gov/oppt/exposure/pubs/episuitedl.htm)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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