Hexafluoropropene, oxidized, oligomers, reduced, fluorinated

Auto flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

auto-ignition temperature (liquids)

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Study period:

2002

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Experimental result obtained on substance with similar chemical structure, according to recognized international standard method.

Justification for type of information:

REPORTING FORMAT FOR THE ANALOGUE APPROACH

1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The hypothesis is that, basing on the structural similarity, experimental data on H-GALDEN can be used in order to get information on the biological behaviour of GALDEN LMW and on certain type of physical-chemical properties. Basing on available data, the source is anticipated to be a worst-case.
The hyphotesis is developed further in the attached "The Read-Across Justification Document".

2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
Target = GALDEN LMW // Source = H-GALDEN
Information on identity, purity and impurities of target and source chemicals is detailed in the attached "The Read-Across Justification Document".

3. ANALOGUE APPROACH JUSTIFICATION
The approach is justified by the structure similarity between GALDEN LMW and H-GALDEN which are both fluoroethers and characterized by the presence of the C-F bond in their entire carbon chains with the exception of the terminal groups in H-GALDEN.
Both the C-F and ether bonds participate in giving the fluoroethers their typical properties in term of thermal and chemical stability but the C-F bond in particular is recognized to increase the stability of the structure. As the C-F bond constitutes the main backbone of the two structures, GALDEN LMW and H-GALDEN are anticipated to have similar stability in term of ignition and thermal degradation.Both GALDEN LMW and H-GALDEN do not flash (no FP untill the BP). H-GALDEN may eventually represent a worst case for physicochemical read across due to the presence of the hydrogen atom in the terminal groups of the molecule (the bond C-H is weaker than the bond C-F) which may make H-GALDEN more sensitive to ignition and thermal degradation than GALDEN LMW.

The use of the information available on H-GALDEN for reading across to GALDEN LMW is considered justifiable becasue for the Auto-ignition temperature endpoint no study is required to be conducted on GALDEN LMW as the substance was determined to not flash until boiling. Basing on this result GALDEN LMW is recognized to be of no concern in regards of its auto-ignition properties and the test does not need to be conducted according to Column 2 adaptation. The experimental data available on H-GALDEN support the lack of concern in regards of auto-ignition up to 600°C.

The analogue approach justification is discussed in the attached "The Read-Across Justification Document".

4. DATA MATRIX
The data matrix is reported in the attached "The Read-Across Justification Document".
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The Read-Across Justification Document is attatched. It is developed according to Read-Across Assessment Framework (RAAF) (ECHA, 2017) and the complementary guidance on considerations on multi-constituent substances and UVCBs (ECHA, 2017)

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

read-across source

GLP compliance:

no

Key result

Auto-ignition temperature:

> 600 °C

Atm. press.:

1 010 mBar

Remarks on result:

not determinable

Remarks:

no autoignition up to the temperature of 600°C

Conclusions:

Based on Read Across with H-GALDEN, it can be affirm that GALDEN LMW shows no self ignition until the temperature of 600 °C.

Executive summary:

The analogue substance H-GALDEN was tested for auto-ignition temperature according to ASTM method No. E 659.

H-GALDEN is a hydrofluoropolyether with similar chain structure and similar molecular weight of GALDEN LMW. The differences between the two substances are the monomer units (the monomer unit in H-GALDEN is (C2F4O) while the monomer unit of GALDEN LMW is (C3F6O) ) and the presence of a single hydrogen atom segregated in the terminal groups of the molecule H-GALDEN.

Basing on the structural similarity, experimental data on H-GALDEN can be used in order to get information on phisico-chemical properties and biological behaviour of GALDEN LMW. It should be noted that the presence of –OCF2H as terminal groups in H-GALDEN, gives to the product slight more reactivity and more polarity than those observed for GALDEN, characterised by neutral, non functional terminal groups –OCF3.

H GALDEN, tested until the temperature of 600 °C under a pressure of 1010 mbar (101000 Pa), showed no autoignition.

Because of the presence of –OCF2H as terminal groups in H GALDEN, which gives to the product more reactivity and more polarity than those observed for GALDEN LMW, the reported read across represents a worst case approach and therefore in conclusion, it can be affirm that GALDEN LMW shows no self ignition until the temperature of 600 °C and under a pressure of 101000 Pa.

Reference 2

Endpoint:

auto-ignition temperature (liquids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a liquid non flammable in air, e.g. no flash point up to 200°C

other:

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING

GALDEN LMW was tested for flash point and fire point determination according to the method ASTM D92 "Standard Test Method for Flash and Fire Points by Cleveland Open Cup Tester” and no flash point and fire point were observed up to the boiling of the test item. GALDEN LMW is therefore a non flammable liquid in air and the auto-ignition test does not need to be conducted.

In addition, as supporting information of absence of auto-ignition, an auto-ignition temperature determination on the analogue substance H GALDEN is reported. The analogue substance H-GALDEN was tested for auto-ignition temperature according to ASTM method No. E 659.
H-GALDEN is a hydrofluoropolyether with similar chain structure and similar molecular weight of GALDEN LMW. The differences between the two substances are the monomer units (the monomer unit in H-GALDEN is (C2F4O) while the monomer unit of GALDEN LMW is (C3F6O) ) and the presence of a single hydrogen atom segregated in the terminal groups of the molecule H-GALDEN. Basing on the structural similarity, experimental data on H-GALDEN can be used in order to get information on physico-chemical properties and the biological behaviour of GALDEN LMW. Moreover, because of the presence of –OCF2H as terminal groups in H-GALDEN, H-GALDEN is more reactive GALDEN LMW which is characterised by neutral, non functional terminal groups –OCF3.
H-GALDEN, tested until the temperature of 600 °C under a pressure of 1010 mbar (101000 Pa), showed no autoignition. Because of the presence of –OCF2H as terminal groups in H GALDEN, the reported read across represents a worst case and therefore in conclusion, it can be affirm that GALDEN LMW is expected to have no auto-ignition until the temperature of 600 °C and under a pressure of 101000 Pa.

Furthermore to support the slight reactivity of GALDEN LMW for self-ignition, the results of a self-ignition determination test conducted at constant temperature and variable oxygen pressure on several products of GALDEN and FOMBLIN families are reported. The test was conducted by a German recognized organization with the purpose to certify materials for the safe use in plants on contact with Oxygen.
GALDEN and FOMBLIN products have the same chemical structure and the only difference is the molecular weight, therefore they can be grouped in the same category. Since the molecular structure is the same, the physical properties depending from molecular weight follow a trend across the category whereas physical properties depending only from the arrangement of chemical structure and from presence/absence of functional groups are the same for the all category members. Experimental results confirm slight reactivity on contact with oxygen of all the members of GALDEN-FOMBLIN category tested.
Since the molecular structure is the same, the same slight reactivity concerning reaction with oxygen is expected for GALDEN LMW.

Description of key information

GALDEN LMW is a non flammable liquid in air and the auto-ignition test does not need to be conducted.

In addition, basing on data available on analogue compound GALDEN LMW is not expected to have auto-ignition until the temperature of 600°C at atmospheric pressure.

Additional information

According to Column 2 of REACH Annex VII the test does not need to be conducted for liquids non flammable in air.

GALDEN LMW was tested for flash point and fire point determination according to the method ASTM D92 "Standard Test Method for Flash and Fire Points by Cleveland Open Cup Tester” and no flash point and fire point were observed up to the boiling of the test item. GALDEN LMW is therefore a non flammable liquid in air and the auto-ignition test does not need to be conducted.

 

In addition, as supporting information of absence of auto-ignition, an auto-ignition temperature determination on the analogue substance H GALDEN is reported. The analogue substance H-GALDEN was tested for auto-ignition temperature according to ASTM method No. E 659.

H-GALDEN is a hydrofluoropolyether with similar chain structure and similar molecular weight of GALDEN LMW. The differences between the two substances are the monomer units (the monomer unit in H-GALDEN is (C2F4O) while the monomer unit of GALDEN LMW is (C3F6O) ) and the presence of a single hydrogen atom segregated in the terminal groups of the molecule H-GALDEN. Basing on the structural similarity, experimental data on H-GALDEN can be used in order to get information on physico-chemical properties and the biological behaviour of GALDEN LMW. Moreover, because of the presence of –OCF2H as terminal groups in H-GALDEN, H-GALDEN is more reactive GALDEN LMW which is characterised by neutral, non functional terminal groups –OCF3.

H-GALDEN, tested until the temperature of 600 °C under a pressure of 1010 mbar (101000 Pa), showed no autoignition. Because of the presence of –OCF2H as terminal groups in H GALDEN, the reported read across represents a worst case and therefore in conclusion, it can be affirm that GALDEN LMW is expected to have no auto-ignition until the temperature of 600 °C and under a pressure of 101000 Pa.