Registration Dossier
Registration Dossier
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EC number: 203-691-9 | CAS number: 109-65-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
- Justification for type of information:
- Please see attached justification for read across in Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Post exposure observation period:
- None
- Key result
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 94.3 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % CL of 82.2 - 178
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 41.1 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % CL of 30.4 - 58.2
- Key result
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- 30.5 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % CL of 21.9 - 43.3
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 24.3 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % CL of 17.7 - 33.3
- Key result
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1.77 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Reference
Description of key information
In an acute toxicity to fish study, Oncorhynchus mykiss were exposed to 1-bromopropane for 96 hours under semi-static conditions in a sealed environment to prevent the volatile test substance from escaping.
The 96-hour LC50 value for 1-bromopropane with rainbow trout was 24.3 mg/L, with 95% confidence limits of 17.7 and 33.3 mg/L.
The No Observed Effect Concentration (NOEC) was 1.77 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 24.3 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
