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EC number: 295-714-4 | CAS number: 92128-22-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
There is no measured data available on aquatic/sediment bioaccumulation for the substance (CAS: 92128-22-8). According to REACH Annex XI, alternative approach should be considered before a new vertebrate test is conducted. The following aspects have been taken into account and in conclusion no aquatic/sediment bioaccumulation test is recommended and the substance is expected to be not bioaccumulative.
- Increased log Kow but low water solubility and, therefore, high potential to surface adsorption and low potential for bioaccumulation. This is supported by high log Koc.
- Experimental study difficult to perform for a UVCB substance.
- Available data on log Kow allow PBT/vPvB assessment and evaluation of B and vB property of the substance. A new experimental study would have no influence on the outcome that the substance is not PBT/vPvB as the substance is not P/vP and not T.
In conclusion, bioaccumulation property may be derived from available log Kow and a new experimental vertebrate study is not expected to be needed.
Key value for chemical safety assessment
- BCF (aquatic species):
- 77.79 L/kg ww
Additional information
Three substances were chosen as representative to allow QSAR estimation of the substance`s bioaccumulation potential: a) and b) are educts and c) is a reaction product.
a) Octadecanoic acid (CAS 57-11-4):
The bioaccumulation factor of octadecanoic acid was estimated to be 10 L/kg using the BCFBAF model included in the EPI-Suite Programm concluding that the substance has alowpotential to bioaccumulate in biota. Within the scope of the Persistency-Bioaccumulation-Toxicity (PBT)-Assessment, the substancedoes not fulfill the B-criterion. Octadecanoic acid falls within the applicability domain described above and, therefore, the predicted value can be considered reliable.
b) 1,3 -Propanediamine, N,N-dimethyl- (CAS 109-55-7):
The bioaccumulation factor of 1,3 -Propanediamine, N,N-dimethyl- was estimated to be 3.162 L/kg using the BCFBAF model included in the EPI-Suite Programm concluding that the substance has a low potential to bioaccumulate in biota. Within the scope of the Persistency-Bioaccumulation-Toxicity (PBT)-Assessment, the substance does not fulfill the B-criterion. 1,3 -Propanediamine, N,N-dimethyl- falls within the applicability domain described above and, therefore, the predicted value can be considered reliable.
c) Fatty acid, tall-oil, compound with N-[3-(dimethylamino)-propyl]-tall-oil amides (CAS 92128-22-8):
The bioaccumulation factor of fatty acid, tall-oil, compound with N-[3-(dimethylamino)-propyl]-tall-oil amides was estimated to be 70.79 L/kg using the BCFBAF model included in the EPI-Suite Programm concluding that the substance has a low potential to bioaccumulate in biota. Within the scope of the Persistency-Bioaccumulation-Toxicity (PBT)-Assessment, the substance does not fulfill the B-criterion. Fatty acid, tall-oil, compound with N-[3-(dimethylamino)-propyl]-tall-oil amides falls within the applicability domain described above and, therefore, the predicted value can be considered reliable.
Concluding, from two educts and a reaction product the highest BCF = 70.79 L/kg is that of the product and this is used for the assessment.
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