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Diss Factsheets
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EC number: 275-702-5 | CAS number: 71617-10-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Guideline:
- other: no data
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Details on test solutions:
- no details
- Test organisms (species):
- Daphnia sp.
- Details on test organisms:
- no details
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Remarks on exposure duration:
- no data
- Dose descriptor:
- EC0
- Effect conc.:
- 1 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Dose descriptor:
- EC100
- Effect conc.:
- 31.6 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Dose descriptor:
- EC50
- Effect conc.:
- 5.6 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: EC50 = EC0/EC100
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In the acute test with daphnia an EC0 of 1 mg/L and and EC100 of 31.6 mg/L was determined. The EC50 was determined by caclulating the geometric mean of the EC0 and EC100. The EC50 is 5.6 mg/L.
No details about the test design (duration, test system, etc.) are known. - Executive summary:
In the acute test with daphnia an EC0 of 1 mg/L and and EC100 of 31.6 mg/L was determined. The EC50 was determined by caclulating the geometric mean of the EC0 and EC100. The EC50 is 5.6 mg/L. No details about the test design (duration, test system, etc.) are known.
Reference
Description of key information
The test substance is acutely toxic to aquatic invertebrates (EC50 = 0.28 mg/L).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.28 mg/L
Additional information
The acute toxicity of the substance was studied in a valid GLP test according to EU Method C.2 (key study). The test was performed under static conditions over a period of 48 hours. The tested daphnia (5 animals per concentration, 2 replicates) were exposed to the test substance at 5 different concentrations (0.056, 0.11, 0.23, 0.45, and 0.9 mg/L) for 48 h.
The highest concentration which did not cause immobilisation after 48 h was 0.1 mg/L (= EC0, arithmetic mean), whereas the concentration that caused 100% immobilisation after 48 h (= EC100, arithmetic mean) was 0.76 mg/L. The geometric mean between the EC0 and the EC100 value, which is considered to represent the EC50 value, was determined at 0.28 mg/L. In the control, no immobilisation occurred at all test concentrations after both exposure periods, ensuring the validity of the test system. The second required validity criterion for the test, a dissolved oxygen concentration > 3 mg/L at the end of the test in control and test vessels, was also fulfilled.
The second acute study with daphnia was probably conducted similar to OECD 202 but as only a result page is available and thus no details on the study are available the reliability of the study could not be assessed and therefore a reliability level of 4 (not assignable) is given to this study. The EC50 (geometric mean of EC0 and EC100) was determined to be 5.6 mg/L.
The effects of the test substance on marine invertebrates were not studied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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