Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-832-9 | CAS number: 88-45-9
Endpoint summary
Administrative data
Description of key information
Hydrolysis
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be > 5 days, at pH range 4, 7 & 9 and a temperature of 50°C or 276 days at pH 7.0, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is not hydrolysable in water.
Additional information
Hydrolysis
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical. The studies are as mentioned below:
The half-life of the test chemical was determined at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C (ranges from 49-51°C) and pH of 4, 7 and 9, respectively. Initial test chemical concentration used for the study was 100 mg/l. Experiment was performed in 2 replicates. The test substance has no activity of hydrolysis and thus was reported to be hydrolytically stable at pH 4, 7 and 9, respectively at a temperature of50⁰C for 5 days. The half-life value of test chemical was determined to be > 5 days at pH 4, 7 and 9, respectively & at a temperature of 50⁰C. Thus based on this, test chemical is considered to be not hydrolysable.
In an another study, the half-life and hydrolysis rate constant was determined of the test chemical. The hydrolysis rate constant of test chemical was determined to be 2.9 х 109 L/mol-sec with a corresponding half-lives of 276 days at pH 7, respectively. Based on the half-life value, it is concluded that the test chemical is not hydrolysable.
For the test chemical, the half-life of the test chemical was determined at different pH range. The preliminary study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C. Initial test chemical conc. Used for the study was 20 mg/l. Analytical method involve the use of HPLC. Although the half-life value of test chemical was not known, but at the preliminary test, the residues of the test chemical were more than 90 % in all the pH. Thus, the test chemical was reported to be stable in water at a temperature of 50⁰C and at pH 4, 7 and 9, respectively. Based on this, it is concluded that the test chemical is not hydrolysable.
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be > 5 days, at pH range 4, 7 & 9 and a temperature of 50°C or 276 days at pH 7.0, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is not hydrolysable in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
