Registration Dossier
Registration Dossier
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EC number: 213-986-4 | CAS number: 1071-22-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72-hour EC50 value of >3.6 mg/L and NOEC of 1.8 mg/L have been determined for the effects of the read-across substance 3-(triethoxysilyl)propiononitrile on growth rate of Pseudokirchnerella subcapitata. The test results are expressed relative to the concentration of the test substance however it is likely that the test organisms were exposed to a mixture of the test substance and its hydrolysis products. The EC50 and NOEC values expressed relative to nominal test concentration are >120 and 60 mg/L respectively.
Key value for chemical safety assessment
Additional information
No data are available for the submission substance,
3-(trichlorosilyl)propiononitrile.
However data are available for the read-across substance3-(triethoxysilyl)propiononitrile.
The hydrolysis half-lives of 3-(trichlorosilyl)propiononitrile and 3-(triethoxysilyl)propiononitrile indicate that, under conditions relevant to ecotoxicity assessment, both will hydrolyse to 3-(trihydroxysilyl)propionitrile. The other hydrolysis products are hydrogen chloride and ethanol, respectively; the properties of these substances are well characterised. Ethanol is non-toxic to the environment and it is considered unlikely that it’s presence significantly affected the results of the test performed with 3-(triethoxysilyl)propiononitrile. Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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