Registration Dossier
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Diss Factsheets
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EC number: 939-249-3 | CAS number: 97926-05-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The test item was irritating to the skin but not irritating to the eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The registered substance was tested in an OECD 404 study for skin irritaing under GLP conditions. One hour after termination the first animal showed a well-defined erythema and a very slight edema. The second animal showed very slight edema and erythema and the third animal showed very slight erythema. All animals showed severe to well-defined erythema and only slight edema. After 48 hours all animal showed erythema and edema ranging from slight to severe. At 72 hours all animals showed moderate to severe erythema and only slight edema. On day 7 scale formation of the whole area was seen for all animals. After 14 days scales were still visible. After 21 days normal hair growth and intact skin were found for all animals. The registered substance is considered to be irritating to the skin (Xi, R38, H315 Cat2).
In a GLP compliant OECD 405 study the registered sustance was tested for eye irritaing. One hour after application if the test article all animals showed slight redness of conjunctivae. One animal additionally showed slight swelling of the conjunctivae. After 24 and 48 hours all animals showed slight redness of conjunctivae and only a slight swelling of conjunctivae was still visible. After 72 hours no eye reactions could be observed any more. The registered substance is considered not to be irritating to the eyes.
Justification for selection of skin irritation / corrosion endpoint:
Klimisch 1 study
Justification for selection of eye irritation endpoint:
Klimisch 1 study
Effects on skin irritation/corrosion: irritating
Justification for classification or non-classification
In accordance with Directive 67/548/EC and Regulation (EC) 1272/2008 the registered susbstance is classified as being irritating to the skin (Xi, R38, H15 Cat2) but being not irritating to the eyes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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