Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: toxicokinetics assessment
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The assessment of the toxicokinetics of Desmodur RC (TDI Trimer) is based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Data source

Reference
Reference Type:
other: Toxicokinetics Assessment
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Principles of method if other than guideline:
assessment on toxicokinetics

Test material

Constituent 1
Reference substance name:
(2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(methyl-m-phenylene) isocyanate
EC Number:
247-840-6
EC Name:
(2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(methyl-m-phenylene) isocyanate
Cas Number:
26603-40-7
Molecular formula:
C27H18N6O6
IUPAC Name:
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione
Constituent 2
Reference substance name:
TDI Trimer
IUPAC Name:
TDI Trimer

Results and discussion

Any other information on results incl. tables

The remarks on the toxicokinetics of Desmodur RC (TDI Trimer) are based on physico-chemical properties of the compound and on toxicological data (Jäger, 2012). Experimental toxicokinetic studies were not performed.

 

Applicant's summary and conclusion