Registration Dossier
Registration Dossier
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EC number: 215-158-8 | CAS number: 1308-14-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Adequacy of study:
- supporting study
- Study period:
- 1991
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from IUCLID dataset, original study not available.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- IUCLID Dataset for: dichromium trioxide hydrate
- Author:
- European Commision
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- Deviations:
- not specified
- GLP compliance:
- yes
- Test type:
- standard acute method
Test material
- Reference substance name:
- Chromium (III) hydroxide
- EC Number:
- 215-158-8
- EC Name:
- Chromium (III) hydroxide
- Cas Number:
- 1308-14-1
- Molecular formula:
- CrH3O3
- IUPAC Name:
- chromium (III) hydroxide
- Reference substance name:
- Chromium hydroxide
- EC Number:
- 235-725-3
- EC Name:
- Chromium hydroxide
- Cas Number:
- 12626-43-6
- IUPAC Name:
- chromium(2+) dihydroxide
- Reference substance name:
- Chromium(III) hydroxide
- IUPAC Name:
- Chromium(III) hydroxide
- Reference substance name:
- Chromium(III) hydroxide
- IUPAC Name:
- Chromium(III) hydroxide
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Dose descriptor:
- LC0
- Effect level:
- > 13.3 other: mg/L
- Exp. duration:
- 4 h
Applicant's summary and conclusion
- Conclusions:
- Acute inhalative toxicity for rats (4h exposition) is LC 0 > 13300 mg/m3
- Executive summary:
In an acute inhalation toxicity study (according to OECD 403 test guideline) rats were exposed by inhalation route for 4 hours to chromium(III) hydroxide. A LC0after 4 hours was estimated to be > 13,300 mg/m3.
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