Oxirane, 2-(2-fluorophenyl)-2-(4-fluorophenyl)-

Guidance on Safe Use

First-aid measures

If inhaled: If experiencing any discomfort, remove to fresh air and obtain medical attention if discomfort does not disappear immediately.

If in eyes: Immediately flush eyes with large amounts of water or eyewash solution, occasionally opening eyelids, until no evidence of chemical remains. Remove contact lenses after a few minutes and flush again. Get medical attention immediately.

If on skin: Immediately remove contaminated clothing and footwear and wash with water and soap. Get medical attention if irritation develops.

If swallowed: Inducing vomiting is not recommended. Let the exposed person rinse mouth and drink a few glasses of water or

milk. If vomiting occurs, rinse mouth and drink fluids again. Get medical attention immediately.

Note to physician: There is no specific antidote against this substance. After decontamination, treatment is symptomatic and supportive as indicated. Gastric lavage and administration of activated charcoal can be considered.

Fire-fighting measures

Extinguishing media: Dry chemical, carbon dioxide, water spray or foam. Avoid heavy hose streams.

Procedures: If required, keep fire-exposed containers cool with water spray. Fight fire from maximum possible distance. In case of large fire, firemen should wear self-contained breathing apparatus and protective clothing.

Hazardous products in a fire: The essential breakdown products are hydrogen fluoride, carbon monoxide, carbon dioxide and various fluorinated organic compounds.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: It is recommended to have a predetermined plan for the handling of spills. Empty, closable vessels for the collection of spills should be available.

In case of large spill (involving 10 tons of the product or more):

1. Use personal protection equipment.

2. Call emergency telephone no.

3. Alert authorities.

Observe all safety precautions when cleaning up spills. Use personal protection equipment. Depending on the magnitude of the spill this may mean wearing respirator, face mask or eye protection, chemical resistant clothing, gloves and boots.

Stop the source of the spill immediately if safe to do so. Keep unprotected persons away from the spill area. Avoid and reduce mist formation as much as possible. Personal exposure by splashing must be avoided.

Environmental precautions: Contain the spill to prevent any further contamination of surface, soil or water. Wash waters must be prevented from entering surface water drains. Uncontrolled discharge into water courses must be alerted to the appropriate regulatory body.

Methods and materials for containment and cleaning up: It is recommended to consider possibilities to prevent damaging effects of spills, such as bunding or capping. See GHS (Annex 4, Section 6).

      

If appropriate, surface water drains should be covered. Minor spills on the floor or other impervious surface should be absorbed onto an absorptive material such as universal binder, bentonite, Fuller’s earth or other absorbent clays. Collect the contaminated absorbent in suitable containers. Clean area with detergent and water. Absorb wash liquid with absorbent and transfer to suitable containers. The used containers should be properly closed and labelled.

      

Spills which soak into the ground should be dug up and transferred to suitable containers.

      

Spills in water should be contained as much as possible by isolation of the contaminated water. The contaminated water must be collected and removed for treatment or disposal.

Handling and storage

The substance is an on-site isolated intermediate and therefore is not supposed to be handled or stored.

Should this happen by accidents or other unforseen situations use the below precautions:

Precautions for safe handling: In an industrial environment it is recommended to avoid all personal contact with the product, if possible by using closed systems with remote system control. The material should always be handled by mechanical means as much as possible. Adequate ventilation or local exhaust ventilation is required. The exhaust gases should be filtered or treated otherwise.

Remove contaminated clothing immediately. Wash thoroughly after handling. Before removing gloves, wash them with water and soap. After work, take off all work clothes and footwear. Take a shower, using water and soap. Wear only clean clothes when leaving job. Wash protective clothing and protective equipment with water and soap after each use.

Do not discharge to the environment. Collect all waste material and remains from cleaning equipment, etc., and dispose of as hazardous waste.

Conditions for safe storage, including any incompatibilities:       The substance is stable under normal conditions of warehouse storage.

Transport information

Shipping

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

Shipping

Special provisions / remarks

Remarks:

Substance is not transported, since it is an onsite isolated intermediate.

Marine transport (UN RTDG/IMDG)

Shipping

Special provisions / remarks

Remarks:

Substance is not transported, since it is an onsite isolated intermediate.

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Substance is not transported, since it is an onsite isolated intermediate.

Additional transport information

Additional information

Special provisions / remarks / other:

Substance is not transported, since it is an onsite isolated intermediate.

Exposure controls / personal protection

Exposure controls: When used in a closed system, personal protection equipment will not be required. The following is meant for other situations, when the use of a closed system is not possible, or when it is necessary to open the system. Consider the need to render equipment or piping systems non-hazardous before opening.

Respiratory protection: In the event of an accidental discharge of the material which produces a vapour or mist, workers must put on officially approved respiratory protection equipment with a universal filter type including particle filter.

      

Protective gloves: Wear chemical resistant gloves, such as barrier laminate, butyl rubber or nitrile rubber. The breakthrough times of these materials for the product are unknown. Generally, however, the use of protective gloves will give only partial protection against dermal exposure. Small tears in the gloves and cross-contamination can easily occur. It is recommended to shift the gloves frequently and to limit the work to be done manually.

Eye protection: Preferably wear a face-mask, rather than goggles or safety glasses. It is recommended to have an eye wash fountain immediately available in the workplace.

      

Other skin protection: Wear appropriate chemical resistant clothing to prevent skin contact depending on the extent of exposure. During most normal work situations where exposure to the material cannot be avoided for a limited time span, waterproof pants and apron of chemical resistant material or coveralls of PE will be sufficient. Coveralls of PE must be discarded after use if contaminated. In cases of appreciable or prolonged exposure, coveralls of barrier laminate may be required.

Stability and reactivity

Reactivity: Reacts with acids.

Heating of the product will produce toxic, flammable and irritant vapours.

Disposal considerations

Waste treatment methods: Remaining quantities of the material and empty but unclean packaging should be regarded as hazardous waste.

Disposal of waste and packagings must always be in accordance with all applicable local regulations.

Disposal of product: According to the Waste Framework Directive (2008/98/EC), possibilities for reuse or reprocessing should first be considered. If this is not feasible, the material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing.

Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Disposal of packaging : Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.