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Diss Factsheets
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EC number: 247-269-2 | CAS number: 25797-81-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1981
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- Comparable to internationally accepted guidelines.
- Deviations:
- no
- Principles of method if other than guideline:
- Method A-11
- GLP compliance:
- no
- Specific details on test material used for the study:
- FAT 20033/G
Purity: approx. 82.2 % - Analytical monitoring:
- no
- Details on sampling:
- None
- Vehicle:
- no
- Details on test solutions:
- none
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- 10 fishes were used per concentration.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- none
- Post exposure observation period:
- none
- Test temperature:
- 25 °C
- pH:
- 8.2 - 8.3
- Dissolved oxygen:
- 6.7 - 7.1
- Nominal and measured concentrations:
- 30, 100 and 300 mg/L
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- other: TL0
- Effect conc.:
- 30 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- other: TL50
- Effect conc.:
- 113 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- other: TL100
- Effect conc.:
- 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- After 96h exposure, 10/10, 7/10 and 0/10 fish survived at 30, 100 and 300 mg/L, respectively.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 96h TL50 of FAT 20033/G in fish acute toxicity test was determined to be 113 mg/L.
- Executive summary:
The acute fish toxicity test was performed using a methodology equivalent or similar to OECD Guideline 203. Groups of fish were exposed to FAT 20033/G for 96 hours at following concentrations: 30, 100 and 300 mg/L.
After 96h exposure, 10/10, 7/10 and 0/10 fishes survived at 30, 100 and 300 mg/L, respectively. Based on the findings of the study, the 96h TL50 of FAT 20033/G in this fish acute toxicity test was determined to be 113 mg/L.
Reference
Description of key information
The 96h LC50 of Acid Blue 277 was determined to be 113 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 113 mg/L
Additional information
A study was conducted to determine the acute toxicity of the test substance (of ca.82.2 %) to zebrafish (Danio rerio). Groups of 10 fishes were exposed at 30, 100 or 300 mg/L for a duration of 96 h. The number of surviving fish was recorded at 4, 24, 48, 72 and 96 h. All fish died within 4 h at the high dose whereas 3 fish died at the intermediate dose and none at the low dose. Under the test conditions, the 96 h LC0 was 30 mg/L (i.e. ca. 25 mg a.i./L), the 96 h LC50 was 113 mg/L (i.e. ca. 93 mg a.i./L) and the 96 h LC100 was 300 mg/L (i.e. ca. 247 mg a.i./L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.