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Diss Factsheets
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EC number: 601-017-1 | CAS number: 110964-79-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- August 10, 2009 - August 14, 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OSPAR Commission 2006: Protocols on Methods for the Testing of Chemicals Used in the Offshore Industry (Part B was amended in 2006 (OSPAR summary record 06/23/1, §9.7))
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-methanesulfonyl-2-nitrobenzoic acid
- EC Number:
- 601-017-1
- Cas Number:
- 110964-79-9
- Molecular formula:
- C8 H7 N O6 S
- IUPAC Name:
- 4-methanesulfonyl-2-nitrobenzoic acid
- Details on test material:
- Substance delivered by Cheminova to DHI August 7, 2009. Stored at room temperature.
Constituent 1
Test organisms
- Test organisms (species):
- other: Scophthalmus maximus
- Details on test organisms:
- Animals were bought from the commercial producer – Maximus at Thisted, Denmark.
Study design
- Water media type:
- saltwater
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 15.9 +- 0.1 C
- pH:
- 8.0
- Dissolved oxygen:
- > 70%
- Salinity:
- 32 o/oo
- Nominal and measured concentrations:
- Nominal: 50; 100; 200; 500 and 1000 mg/l
- Details on test conditions:
- Light/dark period at 16:8 hours
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorphenol (3,5-DCP)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC10
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: No effects were seen
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: No effects were seen
- Details on results:
- The lethality for the control group was at the end of the test less than 10%.
The oxygen saturation for all aquaria were > 60% during the whole test period.
The fish were a little smaller than recommended by OSPAR, since their average length was 3.38 +- 0.30 cm. The average weight was 1.01 +- 0.24 g and in that way the requirement about maximally 1 gram fish per litre test solution is kept. - Results with reference substance (positive control):
- The reference substance was tested at 0.3; 0.6; and 1.2 mg 3,5-DCP. The toxicity was 0% lethality at 0.6 mg/l and 100% at 1.2 mg/l. That is below the recommended 20-80% lethality at 0.6 mg/l, but since the lethality was 100% at 1.2 mg/l the sensitivity of the fish is assessed to be normal.
Applicant's summary and conclusion
- Conclusions:
- Since no effects were seen, the value of both 10% lethality (LC19) and 50% lethality (LC50) are estimated to be > 1000 mg/l.
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