Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-929-8 | CAS number: 4559-86-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The photodegradation of tetrabutyl urea in air by reaction with OH radicals was calculated via EPIWIN v4.00, AOPWIN v1.92. Based on a reaction rate constant of 31.76 x 10E-12 cm³/molecule x s (at 25°C) and a OH radical concentration of 5 x 10E5 radicals/cm³ (24 h d) a half-life t1/2=12.125 h was calculated. According to REACH Regulation (Annex VIII, 9.2.2.1, column II), the study on hydrolysis as a function of pH does not need to be done if the test substance is hardly soluble in water. As could be shown in a study report the performance of the test on hydrolysis was experimentally not possible due to the low water solubility of tetrabutyl urea. The ready biodegradation of tetrabutyl urea was investigated in a study conducted according to OECD Guideline 301 F over a period of 28 days and using activated sludge as inoculum collected from a sewage treatment plant treating mainly municipal wastewater. The test item proved to be not readily biodegradable under the test conditions employed (<=1.3% biodegradation after 28 d). The functional control reached the pass level > 60% after 14 d. In the toxicity control containing both test and reference item 32.2% biodegradation occurred within 14 d thus indicating that the test item was not inhibitory to the inoculum at the concentration tested. The calculation of the bioaccumulation factor BCF via EPIWIN v4.00, BCFBAF v3.00 yielded values of 112 L/kg ww (regression based method) and 166 (dimensionless, Arnot-Gobas method). The soil sorption coefficient Koc was calculated via EPIWIN v4.00, KOCWIN v2.00. The calculations yielded values of 6376 (using the MCI method) and 9441 L/kg at 25°C (using the Kow method). Henry's Law constant was calculated via EPIWIN v4.00, HENRYWIN v3.20. The calculation yielded a value of 0.0257 Pa x m³/mole at 25°C using the bond method. The calculation of Henry's Law constant according to the equation H=vp/ws and using EPIWIN estimates resulted in a Henry's Law constant of 3.58 Pa x m³/mole.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.