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EC number: 205-582-1 | CAS number: 143-07-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Studies on the acute aquatic toxicity of lauric acid (CAS 143-07-7) are available for all three trophic levels (fish, invertebrates and algae), resulting in LC50(96h) of 5.0 mg/L for fish and and EC50(48h) of 3.6 mg/L for daphnia, respectively. The toxicity study on algae showed no effects up to the limit of water solubility.
Chronic fish toxicity data with lauric acid are not available. Therefore chronic fish toxicity data from a surrogate substance, sodium laurate (CAS 629-25-4, C12) are taken into account. From this test it can be concluded, that long-term effects on fish up to the limit of water solubility are also not to be expected for lauric acid.
One long term toxicity study on invertebrates with lauric acid is available (NITE 2001). Since severe deficiencies such as an invalid solvent control, instable test substance concentration, no defined dose-response curve and unknown fate of the test substance had been stated, the study was therefore disregarded. The chronic toxicity on daphnia was assessed based on a study for decanoic acid (CAS 334-48-5) that was conducted recently within an ongoing test programme in cooperation with Fraunhofer Institute IME (FhG) in Schmallenberg/Germany in 2012. In the test no immobilisation occurred throughout the test, neither the mean cumulative offspring was affected by the test substance. NOELR of >= 1.3 mg/L (measured, TWA) was determined that is corresponding to the nominal loading of 5 mg/L. An additional study on chronic invertebrate toxicity with lauric acid is underway in order to overcome methodological deficiencies due to rapid decay of the test substance and to verify the hazard assessment.
The toxicity to microorganisms is covered by read across data from octanoic acid (CAS 124-07-2) which showed no toxic effect (EC10 (18 h) = 912 mg/L). In the light of this study no toxic effects on microorganisms (Pseudomonas putida) can be deduced for lauric acid.
A detailed justification for the grouping of chemicals and read-across is provided in the Chemical Safety Report (CSR, see section 13 of the technical dossier).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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