Registration Dossier
Registration Dossier
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EC number: 618-990-3 | CAS number: 939961-06-5
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study with GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: 79/831/EWG (Teil C)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 301 F draft Oct. 1990
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3-amino-N-(4-carbamoylphenyl)-4-methoxybenzamide hydrochloride
- EC Number:
- 618-990-3
- Cas Number:
- 939961-06-5
- Molecular formula:
- C15H15N3O3xClH
- IUPAC Name:
- 3-amino-N-(4-carbamoylphenyl)-4-methoxybenzamide hydrochloride
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- source: domestic waste water treatment plant Frankfurt/M-Sindlingen
not adapted to the test item or the reference substance
pre-treatment: one week aeration in the nutrient salt solution - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 445 mg/L
- Based on:
- test mat.
- Details on study design:
- BSB-bottles as reaction vessels
incubation in a WTW-BSB-apparatus at 20+-1°C
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- The substances has to be considered as not readily biodegradable .
- Executive summary:
The substance was tested for ready biodegradation according to the guideline 79/831/EWG (part C) and also to the draft of the OECD guideline 301F. Incubation time was 28 days and incubation temperature 20 +-1°C. During that time the oxygen consumption was measured by a respirometer. No oxygen consumption was observed within 28 days.
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