Registration Dossier
Registration Dossier
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EC number: 200-830-5 | CAS number: 75-00-3
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- eye irritation
- Author:
- Vannas S.
- Year:
- 1 954
- Bibliographic source:
- Acta Ophth
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chloroethane
- EC Number:
- 200-830-5
- EC Name:
- Chloroethane
- Cas Number:
- 75-00-3
- Molecular formula:
- C2H5Cl
- IUPAC Name:
- chloroethane
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Results and discussion
In vivo
Results
- Remarks on result:
- other: When placed in the eye of a rabbit, ethyl chloride produced corneal opacity which was attibuted to chemically induced epithelial damage; no further details reported; not classifiable according to current EEC directives;
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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