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EC number: 806-533-2 | CAS number: 1219086-87-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 August 2015 - 9 October 2015
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (2Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)prop-2-enenitrile
- EC Number:
- 806-533-2
- Cas Number:
- 1219086-87-9
- Molecular formula:
- C15 H7 Cl2 F2 N
- IUPAC Name:
- (2Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)prop-2-enenitrile
- Test material form:
- other: solid
- Details on test material:
- Chemical name (IUPAC) (Z)-3-(3-Chloro-2-fluoro-phenyl)-2-(4-chloro-2-fluoro-phenyl)- acrylonitrile
Lot no. FIS201405080058
Molecular formula C15H7Cl2F2N
Molecular mass 310.13 g/mol
Water solubility <0.02 mg/l at 20°C and pH 4.4–6.0, as determined in the course of an OECD 105 study (ACH study no. A15-01329).
Purity 101.2 % (m/m)
Theoretical oxygen demand 2.064 mg O2/mg (calculated according to chapter 5.2 assuming nitrification)
Test item storage at room temperature, protected from light and humidity
Stability Stable under storage conditions
Expiry date 11 June 2016
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 50 mg/L
- Based on:
- ThOD/L
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 20
- Sampling time:
- 10 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Executive summary:
The biodegradability of PAC-Ethenenitrile (CAS no. 1219086-87-9) exposed to microorganisms derived from activated sludge of a municipal sewage treatment plant was investigated under aerobic static exposure conditions.
The biodegradability of PAC-Ethenenitrile based on O2 consumption was calculated to be 22% after 28 days as compared to the theoretical oxygen demand (ThOD).
The biodegradation of PAC-Ethenenitrile reached 20% at the end of the 10-d window. Biodegradation of the test item was observed without any lag-phase.The procedure control sodium benzoate reached 83% biodegradation after 14 days, thus confirming
suitability of inoculum and test conditions.
All validity criteria were fulfilled.
PAC-Ethenenitrile did not reach the pass level of 60% for ready biodegradability in the Manometric Respirometry Test neither within the 10-d window nor after 28 days of incubation, and, therefore, cannot be termed as readily biodegradable.
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