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EC number: 240-383-3 | CAS number: 16291-96-6 An amorphous form of carbon produced by partially burning or oxidizing wood or other organic matter.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010-08-03 to 2010-08-03
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted in accordance OECD no. 121 resp. EU method C.19 under the GLP compliance.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Principles of method if other than guideline:
- HPLC is performed on analytical columns packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. A moderately polar stationary phase based on a silica matrix is used. While passing through the column along with the mobile phase the test substance interacts with the stationary phase. As a result of partitioning between mobile and stationary phases the test substance is retarded. The dual composition of the stationary phase having polar and non-polar sites allows for interaction of polar and non-polar groups of a molecule in a similar way as is the case for organic matter in soil or sewage sludge matrices. This enables the relationship between the retention time on the colum and the adsorption coefficient on organic matter to be established.
- GLP compliance:
- no
- Type of method:
- HPLC estimation method
- Media:
- other: no aplica
Test material
- Reference substance name:
- Charcoal
- EC Number:
- 240-383-3
- EC Name:
- Charcoal
- Cas Number:
- 16291-96-6
- IUPAC Name:
- Carbón vegetal
- Details on test material:
- Name: Charcoal (Probe 2: C-Fix =80.5%)
Batch no.: 29004
Appearance: Charcoal typic
Composition: Charcoal
CAS no.: 16291-96-6
EINECS-no.: 240-383-3
Purity: C-Fix: 80.5%
Expiry date: Dec. 2030
Storage: Room temperature 20 ± 5 °C, keep away from humidity
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
no aplica - Radiolabelling:
- no
Study design
- Test temperature:
- 25 +/- 1 ºC
HPLC method
- Details on study design: HPLC method:
- Pump: Dionex P580 Pump
Injector: Rheodyne 8125)
Column: Reprosil-Pur CN Dr. Maisch, 4.6 mm i.D., 125 mm length, particle size 3 µm
Detector: Dionex, UVD 170S
Column temperature was room temperature, 25 ± 1 °C.
Wavelength for evaluation: 220 nm
Mobile phase: Methanol/water (55/45% v/v)
Batch equilibrium or other method
- Analytical monitoring:
- not required
- Details on sampling:
- no aplica
- Details on matrix:
- no aplica
- Details on test conditions:
- no aplica
Results and discussion
Adsorption coefficient
- Type:
- log Koc
- Value:
- < 1.5
- Temp.:
- 25 °C
Results: HPLC method
- Details on results (HPLC method):
- The log KOC-value of the test item charcoal (Probe 2: C-Fix = 80.5%) lies outside the calibration range obtained with the used reference substances (1.32-5.63) and also outside the determinable log Koc-range of the HPLC screening method (according to OECD guideline 121: 1.5 - 5.0). Therefore, the log KOC of the test item should be stated as < 1.5.
Results: Batch equilibrium or other method
- Adsorption and desorption constants:
- No aplicable
- Recovery of test material:
- No aplicable
- Concentration of test substance at end of adsorption equilibration period:
- No aplicable
- Concentration of test substance at end of desorption equilibration period:
- No aplicable
- Details on results (Batch equilibrium method):
- No aplicable
- Statistics:
- No aplicable
Any other information on results incl. tables
Calculation of the capacity factor k’:
The capacity factor k´ for every peak was calculated as follows:
k' = (tR - t0)/t0
with tR retention time
to dead time (retention time of sodium nitrate)
Calibration log k’ vs. log KOC
The calibration function was drawn up from the six measurements of the capacity factors of the reference items. By plotting the (known) log KOC values of the reference items against the mean log capacity factors and performing linear regression, a calibration function was obtained in the following form:
y = ax + b
Calculation of log KOC:
Using the determined equation of linear regression and the calculated capacity factors for the test item, for each of the three measurements the log KOC was calculated.
Finally, mean and standard deviation of the log KOC were calculated.
Equation of the regression line:
log k’ = 0.2934 * log KOC– 0.32with a correlation coefficient r2 = 0.986.
Test item charcoal (Probe 2: C-Fix =80.5%):
Measurement data
The retention times of the peak obtained after injection of the test item solution are presented in the following table:
Retention times - test item
Peak Test Item |
TR |
|
[min] |
Measurement 1 |
2.270 |
Measurement 2 |
2.256 |
Measurement 3 |
2.236 |
Mean |
2.254 |
Standard deviation |
0.017 |
Calculated values:
Capacity factor k’, log k’, and log KOC- test item
Peak Test Item |
k’ |
logk’ |
log KOC |
Measurement 1 |
0.7606 |
-0.1188 |
0.686 |
Measurement 2 |
0.7497 |
-0.1251 |
0.664 |
Measurement 3 |
0.7342 |
-0.1342 |
0.633 |
Mean |
|
|
0.661 |
Standard deviation |
|
|
0.026 |
log KOCwas calculated from the capacity factor k’ as follows:
log KOC= (log k’ + 0.32) / 0.2934
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- no log Koc values of test item are outside the range of calibration
- Conclusions:
- The log Koc of the test item charcoal (Probe 2: C-Fix = 80.5%) is stated as <1.5.
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