2-octyldodecan-1-ol

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study without analytical monitoring

Qualifier:

according to guideline

Guideline:

other: DIN 38412/09

Deviations:

no

GLP compliance:

yes

Analytical monitoring:

no

Vehicle:

no

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Salinity:

accoding to guideline

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Details on results:

EbC10 (0-72h): 8.9 mg product/l
EbC50 (0-72h): 100 mg product/l
ErC10 (0-72h): 67 mg product/l
ErC50 (0-72h): >100 mg product/l

Validity criteria fulfilled:

yes

Conclusions:

The inhibition of the algae growth rate (cell number) had been determined according to guideline DIN 38412/09. The effect concentration is: ErC50> 100 mg product/l.

Executive summary:

The aquatic toxicity of 1-Dodecanol, 2-octyl- had been determined in the algae test according to guideline DIN 38412/09. The inhibition of the algae growth rate (cell number) revealed an effect concentration of ErC50: >100 mg product/l.

Key value for chemical safety assessment

EC50 for freshwater algae:

100 mg/L

Additional information

2-Octyldodecan-1-ol is a member of the Guerbet Alcohols, which comprises a range of branched long chain alcohols C12-32. It is also structurally related to the substances of the OECD SIDS Long Chain Alcohols (LCA) categories, comprising a range of straight and branched long chain alcohols C6-22. Experimental data for the Guerbet and LCA categories has been evaluated and trends in the environmental fate of long chain alcohols were deduced.

There are three experimental studies available for C12, C16 and C20 Guerbet Alcohols and these indicate for the longer chain alcohols (C16 and C20) low toxicity to algae with effect concentrations of >11.3 and >100 mg/L. 2-Butyloctanol showed toxicity to algae with an ErC50 of 2.1 mg/l. These studies are in agreement with the findings from the OECD SIDS report (described above) where the low solubility limits of the longest chain alcohols are unlikely to exhibit acute (or chronic) toxicity to aquatic organisms. Consequently, no toxicity to algae is expected for Guerbet alcohols with carbon chain lengths >=C16.