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EC number: 203-187-9 | CAS number: 104-23-4
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Fugacity Model by EPI Suite estimation database
- GLP compliance:
- no
- Radiolabelling:
- not specified
- Oxygen conditions:
- other: estimation
- Inoculum or test system:
- not specified
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Reference substance:
- not specified
- Compartment:
- other: water, material (mass) balance
- % Recovery:
- 16.2
- Compartment:
- other: sediment, material (mass) balance
- % Recovery:
- 0.129
- % Degr.:
- 50
- Parameter:
- other: Half life in water
- Sampling time:
- 900 h
- Remarks on result:
- other: 900 hr= 37.5days
- % Degr.:
- 50
- Parameter:
- other: Half life in sediment
- Sampling time:
- 8 100 h
- Remarks on result:
- other: 8100 hrs = 337.5 days
- Compartment:
- water
- DT50:
- 900 h
- Type:
- other: Estimated
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details not available
- Compartment:
- sediment
- DT50:
- 8 100 h
- Type:
- other: Estimated
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details not available
- Transformation products:
- not specified
- Evaporation of parent compound:
- not specified
- Volatile metabolites:
- not specified
- Residues:
- not specified
- Conclusions:
- Estimated half life of test chemical in water was 37.5 days (900hrs) and in sediment estimated to be 337.5 days (8100 hrs). Hence, the test chemical is not persistent in water and sediment.
- Executive summary:
Estimation Programs Interface (EPI Suite, 2018) prediction model was run to predict the half-life in water and sediment for the test compound. The Test chemical If released in to the environment, 16.2% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of the chemical in water is estimated to be 37.5 days (900 hrs.)The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of Test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into sediment is less than 1 %( i.e., reported as 0.129%) indicates that test chemical is not persistent in sediments.
Reference
|
Mass Amount (percent) |
Half-Life (hr) |
Emissions (kg/hr) |
Water |
16.2 |
900 |
1000 |
Sediment |
0.129 |
8.1e+003 |
0 |
|
Fugacity (atm) |
Reaction (kg/hr) |
Advection (kg/hr) |
Reaction (percent) |
Advection (percent) |
Water |
3.5e-020 |
615 |
798 |
20.5 |
26.6 |
Sediment |
3.48e-020 |
0.542 |
0.127 |
0.0181 |
0.00422 |
Description of key information
Estimation Programs Interface (EPI Suite, 2018) prediction model was run to predict the half-life in water and sediment for the test compound. The Test chemical If released in to the environment, 16.2% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of the chemical in water is estimated to be 37.5 days (900 hrs.)The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of Test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into sediment is less than 1 %( i.e., reported as 0.129%) indicates that test chemical is not persistent in sediments.
Key value for chemical safety assessment
- Half-life in freshwater:
- 37.5 d
- at the temperature of:
- 25 °C
- Half-life in freshwater sediment:
- 337.5 d
- at the temperature of:
- 25 °C
Additional information
Estimation Programs Interface (EPI Suite, 2018) prediction model was run to predict the half-life in water and sediment for the test compound. The Test chemical If released in to the environment, 16.2% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of the chemical in water is estimated to be 37.5 days (900 hrs.)The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of Test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into sediment is less than 1 %( i.e., reported as 0.129%) indicates that test chemical is not persistent in sediments.
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