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EC number: 219-606-3 | CAS number: 2478-10-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 Apr 1989 to 13 Apr 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- no analytical monitoring
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Version / remarks:
- Annex V , Directive 79/831 EkdG (4)
- GLP compliance:
- no
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Butanediolmonoacrylate
- Analytical purity: > 94 %
- Solubility in water: > 500 mg at 293 K - Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- - Concentration of stock solution: 100 mg/L
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: originally obtained from the Institute National de Recherche Chimique Appliquee (France) and cultured in the laboratories of BASF since 1978.
- Age at study initiation: 2 - 24 hours
ACCLIMATION CONDITIONS
-Total hardness: 2.7 ± 0.5 mmol/L
- Acid capacity: 0.90 ± 0.1 mmol/L
- Ca/Mg ratio: 4:1
- Oxygen: >2 mg/L
- Type and amount of food: once per day, green algae - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 2.70 ± 0.5 mmol/L
- Test temperature:
- 19 - 21 °C
- pH:
- 7.97 - 8.11
- Dissolved oxygen:
- 8.1 - 9.2 mg/L
- Conductivity:
- 600 - 700 µSiemens/cm
- Nominal and measured concentrations:
- - Nominal test concentraitons: 0 (control), 3.125, 6.25, 12.5, 25.0, 50 and 100 mg/L
- Measured test concentrations: not determined. - Details on test conditions:
- TEST SYSTEM
- Test vessel: centrifuge glasses with flattened bottom
- Fill volume: 10 mL
- No. of organisms per vessel: 5
- No. of vessels per concentration: 4 replicates
- No. of vessels per control: 4 replicates
- Volume per aminal: 2 mL
- Aeration: the test water was aerated with oil-free air until the test water was saturated with oxygen.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Dilution water chemistry: according to the test guideline DIN 38412, part 11
- Ca/Mg ratio: 4:1
- Na/K ratio: 10:1
- Conductivity: 600 - 700 µS/cm
OTHER TEST CONDITIONS
- Photoperiod: 16 hours light (diffuse) and 8 hours darkness
- Light intensity: 5 µE/m² x s
- Wavelength: 400 - 750 nm
EFFECT PARAMETERS MEASURED
Immobility was recorded after 0, 3, 6, 24 and 48 hours. - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 22.53 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% C.L. = 18.8 - 27 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 12.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- After 48 hours, the number of immobile daphnids were determined to be 2, 11, 20 and 20 at test concentrations of 12.5, 25, 50 and 100 mg/L, respectively. See 'Any other information on materials and methods incl. tables'. At the lowest two test concentrations, all daphnids remained mobile during the whole exposure period.
- Reported statistics and error estimates:
- Spearman-Kaerber
- Validity criteria fulfilled:
- not specified
Reference
Table: Number of immobile daphnids determined.
Nominal Conc. (mg/L) |
immobilization of daphnia [n] |
||||
0 h |
3 h |
6 h |
24 h |
48 h |
|
3.125 |
0 |
0 |
0 |
0 |
0 |
6.25 |
0 |
0 |
0 |
0 |
0 |
12.5 |
0 |
0 |
0 |
0 |
2 |
25 |
0 |
0 |
0 |
1 |
11 |
50 |
0 |
0 |
0 |
5 |
20 |
100 |
0 |
0 |
0 |
20 |
20 |
0 (control). |
0 |
0 |
0 |
0 |
0 |
ADDITIONAL EFFECT VALUES
EC50 (24 h) = 57.43 (49.4 - 66.8) mg/L
Description of key information
The 48-h EC50 value is 22.53 mg/L in aquatic invertebrates (Daphnia magna).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 22.53 mg/L
Additional information
The acute toxicity to aquatic invertebrates was determined in a study according to EU Method C.2 (BASF, 1989). In this study, daphnids (D. magna, 20 per concentration) were exposed to nominal concentrations of 0 (control), 3.125, 6.25, 12.5, 25.0, 50 and 100 mg/L for 48 hours under static conditions. Test concentrations were not analytically verified. Immobilization was recorded after test start, 3, 6, 24 and 48 hours exposure. No immobilization was observed in the 3.125 and 6.25 mg/L groups. At a test concentration of 12.5 and 25 mg/L cumulative immobility was 10% and 55%, respectively. Finally, in the 50 and 100 mg/L test group 48-h after exposure 100% immobilization was observed. Based on these findings the 48-h EC50 value was determined at 22.53 mg/L.
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