Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 213-650-7 | CAS number: 998-30-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Endpoint:
- partition coefficient
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2011
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction
- Principles of method if other than guideline:
- The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
- GLP compliance:
- no
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- -2.9
- Temp.:
- 20 °C
- Conclusions:
- A Log Kow of -2.9 was obtained for the substance using an appropriate calculation method. The result is considered to be reliable.
- Endpoint:
- partition coefficient
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2011
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction
- Principles of method if other than guideline:
- The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
- GLP compliance:
- no
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 1.7
- Temp.:
- 20 °C
- Conclusions:
- A Log Kow of 1.7 was obtained for the substance using an appropriate calculation method. The result is considered to be reliable.
Referenceopen allclose all
Estimated value, no data available for temperature and pH
Estimated value, no data available for temperature and pH
Description of key information
Partition coefficient (triethoxysilane): 1.7 (QSAR)
Partition coefficient (silanetriol): -2.9 (QSAR)
Log Kow (ethanol): -0.3
Key value for chemical safety assessment
Additional information
Due to the rapid hydrolysis of the substance (1 hr) the partition coefficient is not required. The Log Kow of 1.7 was obtained for the substance and -2.9 for the hydrolysis product using an appropriate calculation method. The result is considered to be reliable. Although, log Kow is not required for inorganic substances, the prediction is indicative of a high tendency to partition to water for the hydrolysis product.
Ethanol has a measured log Kow of -0.3 (Hansch C 1995).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
