Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Oxidising properties
Administrative data
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-02-01 to 2021-07-14
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)
- Version / remarks:
- 2015
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-[2-[2-methoxy-4-(morpholin-4-yl)-5-nitroanilino]pyrimidin-4-yl]-3-phenyl-1H-pyrazole-4-carbaldehyde
- Cas Number:
- 1903010-39-8
- Molecular formula:
- C25H23N7O5
- IUPAC Name:
- 1-[2-[2-methoxy-4-(morpholin-4-yl)-5-nitroanilino]pyrimidin-4-yl]-3-phenyl-1H-pyrazole-4-carbaldehyde
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Physical state: solid
- Appearance: orange powder
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch (Lot) Number: I20ED2016
- Purity/Composition: 101.5%
- Purity test date : 2020-05-27
- Expiry date: 2022-06-06 (retest date)
- Physical Description: Orange powder
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
- Stability and homogeneity of the test material in the vehicle/solvent under test conditions and during storage: not indicated
- Stability in the medium, i.e. sensitivity of the test material to hydrolysis and/or photolysis: not indicated
- Solubility and stability of the test material in the solvent/vehicle and the exposure medium: not indicated
- Reactivity of the test material with the incubation material used (e.g. plastic ware): not indicated
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
No treatment
OTHER SPECIFICS
- Purity/Composition correction factor: Yes, correction factor is 1.0
Study design
- Contact with:
- powdered cellulose
Results and discussion
Test results (Oxidising solids)open allclose all
- Key result
- Sample tested:
- 4:1 sample-to-cellulose ratio
- Parameter:
- mean burning time
- Result:
- 115 s
- Key result
- Sample tested:
- 1:1 sample-to-cellulose ratio
- Parameter:
- mean burning time
- Result:
- > 180 s
- Sample tested:
- reference: 3:7 mixture potassium bromate + cellulose
- Parameter:
- mean burning time
- Result:
- 124 s
- Sample tested:
- reference: 2:3 mixture potassium bromate + cellulose
- Parameter:
- mean burning time
- Result:
- 62 s
- Sample tested:
- reference: 3:2 mixture potassium bromate + cellulose
- Parameter:
- mean burning time
- Result:
- 32 s
Any other information on results incl. tables
The mean burning time of 4:1 of the test item mixture was less than the mean burning time of the 3:7 (w/w) reference mixture. According to this, the test item has oxidizing properties and is to be classified as Division 5.1 in packing group III.
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 (oxidising solids) based on GHS criteria
- Conclusions:
- Based on the results obtained it was concluded that the test item has oxidizing properties and is classified as a Division 5.1 substance in packing group III.
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