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EC number: 457-320-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1999-09-14 to 1999-09-15
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Remarks:
- but with Molybdenum analyses performed in a non-GLP compliant facility
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.31 mg/L
- Temp.:
- 19.72 °C
- pH:
- ca. 5.2 - ca. 5.7
- Remarks on result:
- other: pH of samples at end of each 'run': 5.2 and 5.7
- Details on results:
- The Mo content of all fractions eluted from the 1st run and 7 out of 8 fractions eluted from the 2nd run was < 0.0250 ppm or <0.31 mg test material/l.
The Mo content of the first fraction from the 2nd run was 0.0636 ppm (0.777 mg test material/l); this value was not used in the calculation of the solubility of MRD-99-422. - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L) Below practical limit of quantitation (PQL)
In a GLP study conducted according to OECD guideline 105, the water solubility of MRD-99-422 (EC# 434-650-5) was less than 0.31 mg/l at 20oC. - Executive summary:
In a GLP study conducted according to OECD guideline 105, the water solubility of MRD-99-422 (EC# 434-650-5) was determined by micro-column elution from Chromosorb WHP carrier at approximately 20oC. Samples eluted from the column were analysed for Mo content by ICP-AES, and the concentration of test material determined after normalisation for dilution factor and Mo content (9.17%) of MRD-99-422.
The water solubility of MRD-99-422 was less than the practical quantitation limit (PQL) of the assay of 0.31 mg/l at 20oC.
In view of the structural and chemical similarities, it is considered that the results of this study can be used for read-across to EC# 457-320-2.
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Water solubility:
- < 0.31 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- > 17 - <= 70 h
- Temp.:
- 20 °C
- pH:
- ca. 6.7
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L) Below practical limit of quantitation (PQL)
In a GLP study conducted according to OECD guideline 105, the water solubility of MRD-99-422 (EC# 434-650-5) was less than 0.31 mg/l at 20oC. - Executive summary:
In a GLP study conducted according to OECD guideline 105, the water solubility of MRD-99-422 (EC# 434-650-5) was determined by micro-column elution from Chromosorb WHP carrier at approximately 20oC. Samples eluted from the column were analysed for Mo content by ICP-AES, and the concentration of test material determined after normalisation for dilution factor and Mo content (9.17%) of MRD-99-422.
The water solubility of MRD-99-422 was less than the practical quantitation limit (PQL) of the assay of 0.31 mg/l at 20oC.
In view of the structural and chemical similarities, it is considered that the results of this study can be used for read-across to EC# 457-320-2.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 April 2004 - 27 May 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.31 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- > 17 - <= 70 h
- Temp.:
- 20 °C
- pH:
- ca. 6.7
- Details on results:
- The calibration was found to be linear over the range of 0 to 2 ppm of standard molybdenum solutions with regression coefficient of 1.0000. The practical limit of quantification was considered to be 0.025 ppm.
The test shows that the water solubility is less than 0.31 mg/L. - Conclusions:
- EC# 457-320-2 was found to have a water solubility of less than 0.31 mg/L at 20 degrees C.
- Executive summary:
The method followed to determine the water solubility of the test substance was in accordance with OECD 105 and to GLP. The test substance was found to have a water solubility of less than 0.31 mg/L at 20 degrees C.
Referenceopen allclose all
Description of key information
EC# 457 -320 -2 was found to have a water solubility study of less than 0.31 mg/L at 20 degrees C in accordance to OECD 105 and to GLP.
Key value for chemical safety assessment
- Water solubility:
- 0.31 mg/L
- at the temperature of:
- 20 °C
Additional information
In a GLP study conducted according to OECD guideline 105, the water solubility of MRD-99-422 (EC# 434-650-5) was found to be also less than 0.31 mg/l at 20oC. In view of the structural and chemical similarities, it is considered that the results of this study can be used for read-across to EC# 457-320-2.
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