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EC number: 617-556-0 | CAS number: 84348-37-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015_01_09 - 2015_01_16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: UN Recommendation on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, Rev. 6 (2015) and UN-Model_Regulations, Rev. 19 (2015), \/Dl 2263 Sheet 1, Grewer-Oven (1990)
- Deviations:
- no
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (2S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid
- EC Number:
- 617-556-0
- Cas Number:
- 84348-37-8
- Molecular formula:
- C10H15NO5
- IUPAC Name:
- (2S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Key result
- Relative self-ignition temperature:
- >= 190 °C
- Remarks on result:
- preliminary test
- Remarks:
- Strongly exothermic behaviour can be observed from a temperature of 190°C; further tests would be necessary
Any other information on results incl. tables
Results:
UN-Transport class 4.2 „self-heating substances“
After an endothermic reaction in the range of approx. 150°C – approx. 180°, a strongly exothermic behaviour can be observed from a temperature of 190°C. The measured temperature increase compared to the thermally inert reference sample (graphite powder) was about 185 K (- 88.15 °C).
In the UN Manual "Transport of Dangerous Goods, Manual of Tests & Criteria", Appendix 6, Chapter 5.2.2, the Grewer Oven Test is specified as a screening method for UN transport class 4.2. With this initial test, it can first be evaluated whether the sample is even suitable as a candidate for class 4.2 or not. If the onset temperature determined in air atmosphere for an exothermic reaction of the sample is >220 °C, further tests for class 4.2 are no longer required. The substance then does not meet the conditions of transport class 4.2. Due to the onset temperature determined here, further tests would be necessary with regard to this transport class.
Additional test with nitrogen:
The examination of the sample under an inert atmosphere (pure nitrogen), on the other hand, showed no exothermic effects up to the maximum test temperature of approx. 480 °C. An exothermic decomposition reaction can thus be clearly ruled out. For self-heating, atmospheric oxygen is mandatory. Since no exothermia occurred during the experiment in the Grewer Oven under nitrogen atmosphere, the input criterion of the aforementioned transport class is not met. The investigated substance does not meet the conditions of UN transport class 4.1 "self-reactive substances".
Applicant's summary and conclusion
- Conclusions:
- Further tests would be necessary.
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