Registration Dossier
Registration Dossier
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EC number: 201-325-2 | CAS number: 81-11-8
Endpoint summary
Administrative data
Description of key information
Short term toxicity to aquatic invertebrates:
Study was conducted to determine effective concentration of test chemical on Daphnia magna for 24 h. The median effective concentration of test chemical was determined to be 210 mg/L.
Toxicity to aquatic algae:
Short term toxicity study was conducted for 72 hrs for determining the effect of test chemical on aquatic algae Selenastrum capricornutum ATCC 22662 (Secondary source, 1996). The study was performed in accordance with the OECD Guideline 201 (Alga, Growth Inhibition Test) in a static system. Total 7 nominal concentrations of test chemical were taken for the study ranging from 10-320 mg/l. Stock solutions were prepared with DMSO (100 mg/l). Controls with and without the vehicle were also setup during the study. On the basis of the effect of test chemical on biomass of the test organism Selenastrum capricornutum ATCC 22662, the 72 hr NOEC and EC50 value was determined to be 32 and 76 mg/l, respectively. Thus, test chemical was considered as toxic to aquatic algae and hence, considered to be classified in 'aquatic chronic category 3' as per the CLP classification criteria.
Additional information
Short term toxicity to aquatic invertebrates:
Test was carried out to determine short term toxicity of test chemical to Daphnia magna in accordance with OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). Study was conducted for 24 hours of exposure period. The median effective concentration of test chemical was determined to be 210 mg/L.
Toxicity to aquatic algae:
Short term toxicity study was conducted for 72 hrs for determining the effect of test chemical on aquatic algae Selenastrum capricornutum ATCC 22662 (Secondary source, 1996). The study was performed in accordance with the OECD Guideline 201 (Alga, Growth Inhibition Test) in a static system. Total 7 nominal concentrations of test chemical were taken for the study ranging from 10-320 mg/l. Stock solutions were prepared with DMSO (100 mg/l). Controls with and without the vehicle were also setup during the study. On the basis of the effect of test chemical on biomass of the test organism Selenastrum capricornutum ATCC 22662, the 72 hr NOEC and EC50 value was determined to be 32 and 76 mg/l, respectively. Thus, test chemical was considered as toxic to aquatic algae and hence, considered to be classified in 'aquatic chronic category 3' as per the CLP classification criteria.
Overall, on the basis of available information of aquatic toxicity studies, it can be concluded that the test chemical was considered as toxic to aquatic organisms at environmental relevant concentrations and hence, considered to be classified in 'aquatic chronic category 3' as per the CLP classification criteria.
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