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Diss Factsheets
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EC number: 470-180-7 | CAS number: 61196-40-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004-02-04 to 2004-02-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Version / remarks:
- 2001
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Radiolabelling:
- no
- Test temperature:
- 25 °C
- Details on study design: HPLC method:
- The chromatographic conditions were the same for the determination of t0, the establishment of the calibration graph and the measurement of the test item.
HPLC equipment: HPLC pump G1312A, autosampler G1313A, column oven G1316A, degaser G1322A and Diode Array Detector G1315B by Agilent;
Stationary phase: LiChrospher 100 CN 5pm by Duratec (18704-02); material: stainless steel, dimensions: 125 mm x4.6 mm column temperature: 25 °C
Mobile Phase: 400 mL acetonitrile + 1600 mL cleaned water, isocratic elution
Flow rate: 1.0 mL/min
Injection volume: 10 µL
Detection wavelength 210 nm
Injection amounts: Dead time marker: 22.5 µg; Calibration substances: 0.72 - 2.24 µg; Test item: 0.70 µg
The dead time marker and the calibration substances were dissolved in acetonitrile and diluted 0.1 to 1 in the mobile phase and injected as single standards twice. The item was dissolved and diluted 0.1 to 1 in the mobile phase and injected as single solution twice. - Key result
- Type:
- log Koc
- Value:
- 1.7
- Temp.:
- 25 °C
- Details on results (HPLC method):
- - Retention times of reference substances used for calibration:
Acetanilline: 3.08 min
Benzamide: 2.54 min
Phenole: 3.00 min
Atrazin: 4.71 min
Monuron: 4.86 min
Triadimenol: 9.66 min
Linuron: 10.19 min
Naphthalene: 10.73 min
- Average retention data for test substance: 3.97 - Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption coefficient of the test item was determined to be logKoc = 1.7 applying the HPLC-method described in the OECD TG 121.
- Executive summary:
The adsorption/desorption coefficient KOC of the test item was assessed according to OECD TG 121 applying the HPLC method. As a result the logKOC of 1.7 was determined.
Reference
Description of key information
According to an OECD TG 121 compliant study, the adsorption/desorption coefficient of the test item was determined to be logKoc = 1.72 at 25 °C (reference 5.4.2-1).
Key value for chemical safety assessment
Additional information
According to an OECD TG 121 compliant study, the adsorption/desorption coefficient of the test item was determined to be logKoc = 1.72 at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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