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EC number: 206-312-5 | CAS number: 326-61-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Differential scanning calorimetry and Capillary method
Test material
- Reference substance name:
- Piperonyl acetate
- EC Number:
- 206-312-5
- EC Name:
- Piperonyl acetate
- Cas Number:
- 326-61-4
- Molecular formula:
- C10H10O4
- IUPAC Name:
- (2H-1,3-benzodioxol-5-yl)methyl acetate
- Reference substance name:
- Piperonyl alcohol
- EC Number:
- 207-808-4
- EC Name:
- Piperonyl alcohol
- Cas Number:
- 495-76-1
- Molecular formula:
- C8H8O3
- IUPAC Name:
- 1,3-benzodioxol-5-ylmethanol
Constituent 1
impurity 1
- Specific details on test material used for the study:
- Batch no.: 18020136
Appearance: colourless liquid
Purity: 99.2% (GC)
Homogeneity: homogeneous
Storage: room temperature (20 ± 5°C)
Results and discussion
Melting / freezing point
- Remarks on result:
- not determinable
Any other information on results incl. tables
No valid result could be detected via DSC measurements. Therefore the test was repeated with the capillary method and a melting point was found in a range from 20.6 °C – 21.7°C.
This contradicted to the results of the pre-test, as the test item was still liquid after storage of 24 hours at 4.1 °C.
For the main test of the capillary method the aluminium block with the capillary, which was filled with the test item, were cooled down for at least 24 hours to the nominal temperature of -20 °C.
Enough energy was put into the test item, so that the test item freezes. For melting the test item needs again energy as well, therefore it comes up to a melting delay.
The more amount of the test item is used the more energy is required for freezing. Therefore the capillary (1-2 mg of the test item) of the Confirmation of Results was frozen after storage time of 24 hours at 3.5 °C which was contrary to the pre-test, where 2-3 mL of the test item were used.
Based on the supercool effect the test item freezes later and based on the melting delay the test item melts later.
No result can be given under these test circumstances.
Applicant's summary and conclusion
- Conclusions:
- According to OECD 102 resp. EU A.1, the determination of the melting point of the test item was performed via DSC (differential scanning calorimetry) and Capillary method.
Unfortunately no valid result could be detected via DSC measurements. Therefore the test was repeated with the capillary method.
A melting range from 20.6 °C – 21.7 (293.8 – 294.9 K) was determined but this result contradicted the results of the pre-test, as the test item was still liquid after storage of 24 hours at 4.1°C.
These is caused by the supercool effect and melting delay of the test item.
Referring to the supercool effect and melting delay it is not possible to state a result with both methods under these test circumstances.
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