4-nitrosophenol

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

28 day study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Data taken from a review of nitro-phenol.
Various methods have been cited and this class shows good biodegradation under the standard methods used for chemical safety assessment

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)

Version / remarks:

Described as 'Sturm test'

GLP compliance:

not specified

Specific details on test material used for the study:

No specific details on purity
4-Nitrophenol considered suitable for read-across potential for biodegradation as the oxidation form of the nitrogen is not critical for degradation characteristics.

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, non-adapted

Duration of test (contact time):

28 d

Initial conc.:

ca. 10 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

CO2 evolution

Key result

Parameter:

% degradation (CO2 evolution)

Value:

90

Sampling time:

28 d

Details on results:

The review document does not provide result for interim times, so it is unlear if 10 day window was acheived in this key study.
The review document concludes that the class of substance is 'readily' biodegrable and this result is itself prediced.

Validity criteria fulfilled:

not specified

Interpretation of results:

readily biodegradable

Conclusions:

Data taken from a review of nitro-phenol.
Various methods have been cited and this class shows good biodegradation under the standard methods used for chemcial safety assessment
The review document does not provide result for interim times, so it is unlear if 10 day window was acheived in this key study.
The review document concludes that the class of substance is 'readily' biodegrable and this result is itself prediced.

Description of key information

Data taken from a review of nitro-phenol.

Various methods have been cited and this class shows good biodegradation under the standard methods used for chemcial safety assessment

The review document does not provide result for interim times, so it is unlear if 10 day window was acheived in this key study.

The review document concludes that the class of substance is 'readily' biodegrable and this result is itself prediced.

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Type of water:

freshwater