Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Data waiving:
study technically not feasible
Justification for data waiving:
other:
Justification for type of information:
The test is technically not feasible. The test was attempted but the experimental phase was discontinued since the level of test item ‘interference’ is not compatible with this test.
A preliminary solubility trial was performed using water for injection, dimethylsulfoxide, ethanol and acetone. Suspensions feasible for treatment were obtained in water and were used in the preliminary toxicity test. At the end of the incubation a severe microbial interference was observed in all test item treated plates, hence evaluation of the background lawn and scoring of revertant colonies was not possible.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion