Registration Dossier
Registration Dossier
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EC number: 949-050-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
LC50 fish (96h): > 100 mg/L
EC50 daphnia (48 h) = 7.63 mg/L
EbC 50 algae (72 h) : 196 mg/L
Additional information
According to the CLP Regulation (EC 1272/2008), acute aquatic toxicity is normally determined using a fish 96-hour LC50, a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50; nevertheless it is also specified in the Regulation that data on other species (e. g. Lemna spp.) shall also be considered if the test methodology is suitable. These species cover a range of trophic levels and are considered as surrogate for all aquatic organisms.
According to the table 4.1.0 of the CLP Regulation (EC n. 1272/2008), asubstance for wich adequate chronic toxicity data are not available shall be classified as
Aquatic Acute 1 when:
96 hr LC50 (for fish)≤1 mg/l and/or
48 hr EC50 (for crustacea)≤1mg/l and/or
72 or 96 hr ErC (for algae or other aquatic plants)≤1 mg/l
Aquatic Chronic 1 when:
96 hr LC50 (for fish)≤1 mg/l and/or
48 hr EC50 (for crustacea)≤1mg/l and/or
72 or 96 hr ErC (for algae or
other aquatic plants)≤1 mg/l
Aquatic Chronic 2 when:
96 hr LC50 (for fish) > 1 <= 10 mg/l and/or
48 hr EC50 (for crustacea)> 1 <= 10 mg/l and/or
72 or 96 hr ErC (for algae or
other aquatic plants)> 1 <= 10 mg/l
Aquatic Chronic 3 when:
96 hr LC50 (for fish) > 10 <= 100 mg/l and/or
48 hr EC50 (for crustacea)> 10 <= 100 mg/l and/or
72 or 96 hr ErC (for algae or other aquatic plants)> 10 <= 100 mg/l
and the substance is not rapidly
degradable and/or the experimentally determined BCF ≥ 500 (or, if
absent, the log K ow ≥ 4
The tests results are reported below:
- Acute fish toxicity was investigated
following OECD 203 and gave a LC 50 > 100 mg/l.
- Toxicity to aquatic invertebrates was investigated following the OECD
Guideline 202 (Daphnia Magna Acute Immobilisation Test).
Based on the test results, the tested substance showed some toxic
effects on Daphnids and the EC50 (48 h) was set at 7.63 mg/l.
- The inhibitory effects of the tested substance to the duckweed Lemna minor were investigated over a period of 7 days, based on the frond number and biomass (dry weight), following the guideline OECD 221. Based on the test results, the EC50 value was set at 196 mg/L and the NOEC value was set to 6.38 mg/l.
Based on the test results, the substance shoul be classified as Aquatic Chronic 2, H411: Toxic to aquatic life with long lasting effects.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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