Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
yes (incl. QA statement)
Type of method:
other: In a pre-test, the test item Isoamyl nitrit was still unfrozen and liquid at – 80 °C. No additional has been performed.

Test material

Constituent 1
Chemical structure
Reference substance name:
''amyl nitrite'', mixed isomers
EC Number:
203-770-8
EC Name:
''amyl nitrite'', mixed isomers
Cas Number:
110-46-3
Molecular formula:
C5H11NO2
IUPAC Name:
pentyl nitrite

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
< -80 °C
Atm. press.:
1 atm
Remarks on result:
other: In a pre-test, the test item Isoamyl nitrit was still unfrozen and liquid at – 80 °C.

Applicant's summary and conclusion

Conclusions:
In a pre-test, the test item Isoamyl nitrite was still unfrozen and liquid at – 80 °C.
According to REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL, Annex VII, dated 18. December 2006 (and further amendments) by Commission Regulation the determination of the melting- / freezing point does not need to be conducted below a lower limit of - 20 °C.
Therefore, no additional test was conducted and the freezing point is stated as:
< - 80 °C (< 193.15 K).
Executive summary:

This study was performed in order to determine the melting point or the melting range of the test item Isoamyl nitrite.

The melting point is one of the fundamental physico-chemical properties of a chemical substance. The test item should have been heated with a defined heating rate until melting / decomposition of the test item could has been observed.

In a pre-test, the test item Isoamyl nitrite was still unfrozen and liquidat – 80 °C.

According to REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL, Annex VII, dated 18. December 2006 (and further amendments) by Commission Regulationthe determination of the melting- / freezing point does not need to be conducted below a lower limit of - 20 °C.

Therefore, no additional test was conducted and the freezing point is stated as:

< - 80 °C (< 193.15 K).